TRPC6 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hyperforin dicyclohexylammonium salt | 238074-03-8 | sc-202178 sc-202178A | 500 µg 1 mg | $140.00 $184.00 | 1 | |
Hyperforin dicyclohexylammonium salt acts as a potent modulator of the TRPC6 ion channel, characterized by its unique ability to stabilize channel conformations. This compound facilitates calcium influx through TRPC6, influencing downstream signaling cascades. Its interaction kinetics are notable, with a rapid onset of action and a prolonged effect, allowing for detailed exploration of TRPC6's role in cellular excitability and ion homeostasis. The compound's distinct molecular architecture contributes to its specificity in targeting TRPC6 over other channels. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is known to activate protein kinase C, which can subsequently induce TRPC6 expression. The activation of TRPC6 contributes to various cellular functions, including the regulation of ion balance and signal transduction. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
This active form of vitamin D can bind to the vitamin D receptor, influencing the expression of numerous genes, including TRPC6. It plays a significant role in calcium homeostasis and may contribute to the regulation of TRPC6 expression. | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $51.00 $100.00 $310.00 $690.00 | 3 | |
Angiotensin II binds to its receptors, leading to the activation of multiple signaling pathways. This can result in the upregulation of TRPC6 expression, influencing processes like vasoconstriction and blood pressure regulation. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin can activate various signaling pathways, leading to the regulation of glucose metabolism and other cellular processes. TRPC6 expression has been linked to insulin signaling, potentially playing a role in glucose uptake and metabolism. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin is a serine protease that plays a central role in hemostasis. It has been observed to induce TRPC6 expression, potentially influencing platelet activation and clot formation. | ||||||
Bradykinin | 58-82-2 | sc-507311 | 5 mg | $110.00 | ||
Bradykinin is a peptide that can bind to its receptors, leading to the activation of multiple signaling pathways. This can result in the upregulation of TRPC6 expression, influencing processes like inflammation and pain perception. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
H2O2 is a reactive oxygen species that can act as a signaling molecule. It has been observed to induce TRPC6 expression, potentially playing a role in oxidative stress responses and cellular defense mechanisms. | ||||||
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $38.00 $198.00 $65.00 | 5 | |
High levels of glucose can activate various signaling pathways, influencing the expression of numerous genes. TRPC6 has been linked to glucose metabolism, and its expression may be modulated by glucose levels, potentially influencing cellular responses to glucose. | ||||||