Date published: 2026-5-24

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TRNT1 Activators

TRNT1 activators represent a class of compounds that exert their biological effects by modulating the activity of the enzyme known as tRNA nucleotidyltransferase 1 (TRNT1). TRNT1 is a vital enzyme in the process of tRNA (transfer RNA) maturation, which plays a pivotal role in protein synthesis within cells. Transfer RNAs are essential molecules that carry amino acids to the ribosome, the cellular machinery responsible for assembling proteins. TRNT1 catalyzes the addition of nucleotides to the 3' end of tRNA molecules, ensuring their proper functionality. Activation of TRNT1 involves enhancing its enzymatic activity, which subsequently promotes the efficient maturation of tRNAs.

The discovery and development of TRNT1 activators have garnered significant attention in the field of molecular biology and cellular physiology. These compounds are designed to fine-tune the regulation of tRNA processing by enhancing TRNT1's catalytic capabilities. By doing so, they contribute to the optimization of protein synthesis, which is a fundamental process underlying various cellular functions, including cell growth, differentiation, and response to environmental stimuli. The modulation of TRNT1 activity through activators represents a promising avenue for research into understanding the intricacies of protein synthesis regulation at the molecular level.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a polyphenolic compound that has been shown to influence various genes and signaling pathways. It might activate the expression of TRNT1 as part of its broader effects on gene regulation.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin, a major component of turmeric, is known for its gene-modulatory abilities. Its activation of TRNT1 expression may be related to its broad cellular and molecular interactions.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Found in cruciferous vegetables, sulforaphane can influence the expression of various genes. Its potential activation of TRNT1 could be due to its role in cellular stress responses.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein, an isoflavonoid, has the ability to regulate gene expression. It may increase TRNT1 levels through its interactions with cellular pathways.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

As a flavonoid, quercetin has various cellular effects. Its potential role in TRNT1 activation could be associated with its ability to modulate several signaling pathways.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

Berberine, an alkaloid, has demonstrated the ability to increase gene expression. Its effects on TRNT1 might be a result of its broad cellular interactions.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is a prominent catechin from green tea. It has various cellular effects, and its positive effects on TRNT1 could be linked to its gene-modulatory properties.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin is known to activate adenylate cyclase, leading to increased cAMP levels. The increased cAMP might increase the expression of various genes, including TRNT1.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, a vitamin A derivative, can regulate gene expression. Its potential activation of TRNT1 may be related to its role in cellular differentiation and growth.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone, a glucocorticoid, has been shown to influence the expression of numerous genes. Its agonist role in TRNT1 expression could be a result of its broad cellular effects.