Trk B Activators
SEE ALSO...
Items 1 to 10 of 14 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
7,8-Dihydroxyflavone | 38183-03-8 | sc-278634 | 100 mg | $52.00 | 2 | |
7,8-Dihydroxyflavone is a flavone compound that acts as an agonist for the TrkB receptor. It mimics the action of BDNF, activating downstream cellular processes like neuronal survival and synaptic plasticity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride has been shown to induce Trk B expression through GSK3β inhibition. By inhibiting GSK3β, it modulates various transcription factors, which may then upregulate the expression of Trk B. | ||||||
Demethylasterriquinone B1 | 78860-34-1 | sc-203025 | 5 mg | $510.00 | 2 | |
Demethylasterriquinone B1 (CAS 78860-34-1) is a chemical that activates the TrkB receptor, a crucial player in neuronal survival and synaptic plasticity. By binding to TrkB, it triggers downstream signaling pathways, mimicking the role of its natural ligand, BDNF. The compound is commonly used in research to explore these biological mechanisms. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid, a histone deacetylase inhibitor, may increase Trk B expression by promoting histone acetylation near the NTRK2 gene promoter, thus making it easier for transcription machinery to access. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can induce differentiation of various cell types, including neurons. During this process, Trk B expression is often upregulated, possibly through retinoic acid receptors. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates SIRT1, which in turn can modulate transcription factors and potentially lead to increased Trk B expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases cellular cAMP levels, which can activate protein kinase A. This may result in the phosphorylation and activation of CREB, a transcription factor that can upregulate Trk B expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has anti-inflammatory properties and can activate various signaling pathways, including those involving transcription factors that may upregulate Trk B. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine inhibits phosphodiesterases leading to increased cAMP, which may induce Trk B expression through the activation of PKA and subsequent CREB phosphorylation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is another histone deacetylase inhibitor that can promote histone acetylation, possibly leading to increased transcription of Trk B. | ||||||