Date published: 2026-5-5

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TREM-2 Antibodies

Santa Cruz Biotechnology delivers a wide array of TREM-2 monoclonal antibodies for research in understanding TREM-2's role in various biological processes. TREM-2 monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TREM-2, or Triggering Receptor Expressed on Myeloid Cells 2, is a crucial protein involved in the immune response and has been implicated in neurodegenerative diseases, including Alzheimer's disease. TREM-2 plays a significant role in modulating inflammation and promoting the survival of neurons, making it a key target for therapeutic interventions. Research has shown that TREM-2 expression is particularly important in microglia, where it helps regulate phagocytosis and inflammatory responses. Recent studies have highlighted TREM-2's involvement in various neurological conditions, making it an increasingly important focus of research. Understanding TREM-2's function is essential for elucidating its potential as a biomarker and therapeutic target in various pathologies. TREM-2 research using Santa Cruz Biotechnology monoclonal antibodies continues to advance scientific understanding of neurodegenerative diseases and immune system regulation.

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TREM-2 Antibodies

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TREM-2 Antibody (B-3)

sc-373828mouse IgG1 κ1-160 (h)WB, IP, IF, ELISAh
31
(14)

TREM-2 CRISPR Knockout, HDR and Double Nickase Plasmids

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TREM-2 CRISPR/Cas9 KO Plasmid (h)

sc-401585hGene KnockoutGFP0
(0)

TREM-2 HDR Plasmid (h)

sc-401585-HDRhHomology Directed RepairPuromycin0
(0)

TREM-2 Double Nickase Plasmid (h)

sc-401585-NIChGene KnockoutPuromycin0
(0)

TREM-2 Double Nickase Plasmid (h2)

sc-401585-NIC-2hGene KnockoutPuromycin0
(0)

TREM-2 CRISPR/Cas9 KO Plasmid (m2)

sc-429903-KO-2mGene KnockoutGFP
1
(0)

TREM-2 HDR Plasmid (m2)

sc-429903-HDR-2mHomology Directed RepairPuromycin
1
(0)

TREM-2 Double Nickase Plasmid (m)

sc-429903-NICmGene KnockoutPuromycin
1
(0)

TREM-2 Double Nickase Plasmid (m2)

sc-429903-NIC-2mGene KnockoutPuromycin
1
(0)

TREM-2 CRISPR Activation Products

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TREM-2 CRISPR Activation Plasmid (h)

sc-401585-ACThGene ActivationPuro, Blast, Hygro0
(0)

TREM-2 Lentiviral Activation Particles (h)

sc-401585-LAChGene ActivationPuro, Blast, Hygro0
(0)

TREM-2 CRISPR Activation Plasmid (m)

sc-429903-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

TREM-2 CRISPR Activation Plasmid (m2)

sc-429903-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

TREM-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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TREM-2 siRNA (h)

sc-43001hGene SilencingN/A0
(0)

TREM-2 shRNA Plasmid (h)

sc-43001-SHhGene SilencingPuromycin0
(0)

TREM-2 shRNA (h) Lentiviral Particles

sc-43001-VhGene SilencingPuromycin0
(0)

TREM-2 siRNA (m)

sc-45369mGene SilencingN/A
2
(0)

TREM-2 shRNA Plasmid (m)

sc-45369-SHmGene SilencingPuromycin
2
(0)

TREM-2 shRNA (m) Lentiviral Particles

sc-45369-VmGene SilencingPuromycin
2
(0)