TR α Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $41.00 $77.00 $153.00 | ||
L-3,3′,5-Triiodothyronine, free acid is the active form of thyroid hormone and binds directly to TRα, inducing conformational changes that facilitate the transcription of target genes. | ||||||
3,3′,5-Triiodo-L-thyronine sodium salt | 55-06-1 | sc-231968 sc-231968A sc-231968B | 100 mg 500 mg 1 g | $90.00 $245.00 $439.00 | ||
3,3',5-Triiodo-L-thyronine sodium salt exhibits unique interactions with thyroid hormone receptors, particularly influencing gene expression through its affinity for the TR alpha isoform. Its triiodinated structure enhances lipophilicity, facilitating cellular uptake and nuclear translocation. The compound's distinct binding kinetics promote selective modulation of metabolic pathways, while its conformational adaptability allows for nuanced interactions with co-regulators, impacting transcriptional activity in target tissues. | ||||||
L-Thyroxine, free acid | 51-48-9 | sc-207813 sc-207813A | 100 mg 500 mg | $35.00 $74.00 | 2 | |
L-Thyroxine, free acid is a prohormone and a precursor to T3. It can indirectly activate TRα after being converted to T3 in peripheral tissues. | ||||||
3,3′,5,5′-Tetraiodothyroacetic acid | 67-30-1 | sc-231969 sc-231969A sc-231969B sc-231969C sc-231969D | 25 mg 50 mg 100 mg 250 mg 500 mg | $120.00 $162.00 $277.00 $526.00 $942.00 | 3 | |
3,3',5,5'-Tetraiodothyroacetic acid acts at the thyroid hormone receptor on the plasma membrane, not the nuclear receptor, modulating pathways influenced by TRα. | ||||||
3,5-Diiodo-L-thyronine | 1041-01-6 | sc-216601 sc-216601A sc-216601B sc-216601C sc-216601D | 1 g 5 g 10 g 25 g 100 g | $270.00 $562.00 $938.00 $1408.00 $2673.00 | 2 | |
3,5-Diiodo-L-thyronine has partial agonist activity on TRα, modulating cardiovascular and metabolic processes. | ||||||
L-3,3′,5-Triiodothyronine, Sodium Salt | 55-06-1 | sc-205725 | 250 mg | $115.00 | ||
This is the sodium salt of T3 and acts similarly by binding and activating TRα, influencing metabolic and developmental processes. | ||||||
3,3′,5-Triiodothyroacetic acid | 51-24-1 | sc-226208 | 100 mg | $67.00 | 1 | |
Tiratricol is a thyroid hormone metabolite that shows selective activity on TRα, influencing energy metabolism and thermogenesis. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can indirectly influence TRα activity through cAMP-responsive pathways. | ||||||