Topo II Inhibitors

Santa Cruz Biotechnology now offers a broad range of Topo II Inhibitors for use in various applications. Topo II Inhibitors are a class of compounds that target the enzyme topoisomerase II, a crucial player in DNA replication and transcription. By inhibiting this enzyme, these compounds interfere with the topological state of DNA, preventing the unwinding and rewinding processes essential for various cellular functions. In scientific research, Topo II Inhibitors are invaluable tools for studying cell cycle regulation, gene expression, and the mechanisms underlying DNA damage and repair. Researchers utilize these inhibitors to dissect the roles of topoisomerase II in chromosomal condensation, segregation, and the maintenance of genomic stability. Additionally, these compounds are used in genetic studies to induce mutations and investigate DNA-protein interactions, providing insights into fundamental biological processes. Topo II Inhibitors also serve as probes in biochemical assays to explore the dynamics of DNA topoisomerases and their interactions with other cellular components. Their application extends to biotechnology fields, where they aid in the development of new methodologies for DNA manipulation and analysis. View detailed information on our available Topo II Inhibitors by clicking on the product name.