TNFα-IP 8 inhibitors, also known as Tumor Necrosis Factor Alpha-Induced Protein 8 inhibitors, belong to a distinct chemical class of compounds designed to target a specific molecular pathway in the human body. These inhibitors are meticulously engineered to interact with and modulate the activity of TNFα-IP 8, a protein known for its pivotal role in regulating inflammatory responses and cell survival. TNFα-IP 8 itself is a cytoplasmic protein expressed in various tissues, including immune cells, where it plays a crucial part in modulating the immune system's response to external threats such as infections and tissue damage. By targeting TNFα-IP 8, these inhibitors hold the potential to influence key cellular processes.
The design of TNFα-IP 8 inhibitors involves the development of small molecules or biologics that can either block or enhance the function of TNFα-IP 8. These inhibitors act at the molecular level, often binding to the active sites or interacting with regulatory regions of the TNFα-IP 8 protein. Through this targeted approach, they can modulate cellular signaling pathways, thereby affecting the outcome of immune responses and other physiological processes. The intricate mechanisms underlying TNFα-IP 8 inhibition highlight the importance of this chemical class in advancing our understanding of cell signaling pathways and their potential applications in various fields, although it's essential to note that these compounds should be carefully studied and evaluated for their safety and efficacy before any consideration of broader usage.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Leflunomide | 75706-12-6 | sc-202209 sc-202209A | 10 mg 50 mg | $20.00 $81.00 | 5 | |
Leflunomide is a small molecule inhibitor that indirectly impacts TNFα production by modulating immune cell activation. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Thalidomide is a small molecule with immunomodulatory properties that can inhibit TNFα production and reduce inflammation. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate is an antimetabolite that suppresses immune responses and may be used alongside TNF inhibitors to enhance their effectiveness. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
Sulfasalazine is a small molecule drug, with potential effects on TNFα and inflammation. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $41.00 $133.00 $663.00 | 2 | |
Prednisone is a corticosteroid that broadly suppresses immune responses, indirectly inhibiting TNFα production by reducing inflammation. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
Tacrolimus is an immunosuppressant that indirectly affects TNFα-related inflammation by inhibiting T-cell activation. | ||||||
Cyclosporine | 79217-60-0 | sc-358111 sc-358111A | 100 mg 1 g | $191.00 $992.00 | 2 | |
Cyclosporine is an immunosuppressive drug that primarily inhibits T-cell activation, potentially impacting TNFα-related inflammatory pathways. |