Date published: 2025-9-9

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TNFα-IP 8 Inhibitors

TNFα-IP 8 inhibitors, also known as Tumor Necrosis Factor Alpha-Induced Protein 8 inhibitors, belong to a distinct chemical class of compounds designed to target a specific molecular pathway in the human body. These inhibitors are meticulously engineered to interact with and modulate the activity of TNFα-IP 8, a protein known for its pivotal role in regulating inflammatory responses and cell survival. TNFα-IP 8 itself is a cytoplasmic protein expressed in various tissues, including immune cells, where it plays a crucial part in modulating the immune system's response to external threats such as infections and tissue damage. By targeting TNFα-IP 8, these inhibitors hold the potential to influence key cellular processes.

The design of TNFα-IP 8 inhibitors involves the development of small molecules or biologics that can either block or enhance the function of TNFα-IP 8. These inhibitors act at the molecular level, often binding to the active sites or interacting with regulatory regions of the TNFα-IP 8 protein. Through this targeted approach, they can modulate cellular signaling pathways, thereby affecting the outcome of immune responses and other physiological processes. The intricate mechanisms underlying TNFα-IP 8 inhibition highlight the importance of this chemical class in advancing our understanding of cell signaling pathways and their potential applications in various fields, although it's essential to note that these compounds should be carefully studied and evaluated for their safety and efficacy before any consideration of broader usage.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Leflunomide

75706-12-6sc-202209
sc-202209A
10 mg
50 mg
$20.00
$81.00
5
(1)

Leflunomide is a small molecule inhibitor that indirectly impacts TNFα production by modulating immune cell activation.

Thalidomide

50-35-1sc-201445
sc-201445A
100 mg
500 mg
$109.00
$350.00
8
(0)

Thalidomide is a small molecule with immunomodulatory properties that can inhibit TNFα production and reduce inflammation.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate is an antimetabolite that suppresses immune responses and may be used alongside TNF inhibitors to enhance their effectiveness.

Sulfasalazine

599-79-1sc-204312
sc-204312A
sc-204312B
sc-204312C
1 g
2.5 g
5 g
10 g
$60.00
$75.00
$125.00
$205.00
8
(1)

Sulfasalazine is a small molecule drug, with potential effects on TNFα and inflammation.

Prednisone

53-03-2sc-205816
sc-205816A
sc-205816B
1 g
5 g
25 g
$41.00
$133.00
$663.00
2
(1)

Prednisone is a corticosteroid that broadly suppresses immune responses, indirectly inhibiting TNFα production by reducing inflammation.

FK-506

104987-11-3sc-24649
sc-24649A
5 mg
10 mg
$76.00
$148.00
9
(1)

Tacrolimus is an immunosuppressant that indirectly affects TNFα-related inflammation by inhibiting T-cell activation.

Cyclosporine

79217-60-0sc-358111
sc-358111A
100 mg
1 g
$191.00
$992.00
2
(1)

Cyclosporine is an immunosuppressive drug that primarily inhibits T-cell activation, potentially impacting TNFα-related inflammatory pathways.