Date published: 2026-5-16

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TMEM34 Inhibitors

TMEM34 Inhibitors belong to a class of chemical compounds designed to target and modulate the activity of TMEM34, or Transmembrane Protein 34. TMEM34 is a transmembrane protein, which means it spans the cell's lipid bilayer, with portions of the protein extending both inside and outside the cell. The precise functions and roles of TMEM34 in cellular biology are still the subject of ongoing research, and its exact molecular mechanisms are not fully elucidated. However, TMEM34 is believed to be involved in various cellular processes due to its presence on the cell membrane and its interactions with other proteins or molecules. Inhibitors of TMEM34 are developed to interact with this specific protein, potentially influencing its functions, cellular localization, or interactions with other biomolecules.

Structurally, TMEM34 inhibitors are designed to bind to specific regions or binding sites on the TMEM34 protein. This interaction can disrupt the normal functioning of TMEM34, potentially affecting its participation in cellular processes, signaling pathways, or its interactions with other cellular components. The study of TMEM34 inhibitors and their interactions with the TMEM34 protein can contribute to a deeper understanding of the roles and functions of TMEM34 in cellular biology. It may also provide insights into its potential implications in health and disease. Research into TMEM34 and its modulation by inhibitors can contribute to the broader field of molecular and cellular biology by revealing the complex interplay of proteins and molecules within cells, shedding light on their roles in various physiological processes.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Cycloheximide is a general protein synthesis inhibitor. By inhibiting protein synthesis, it could potentially reduce the expression of TMEM34.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

This compound disrupts protein transport from the endoplasmic reticulum to the Golgi apparatus, which could affect the processing and localization of transmembrane proteins.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$155.00
$525.00
(1)

A sodium ionophore that disrupts transmembrane ion gradients and could influence the function or localization of transmembrane proteins.

Filipin III

480-49-9sc-205323
sc-205323A
500 µg
1 mg
$118.00
$148.00
26
(2)

Filipin binds to cholesterol, disrupting lipid rafts in cellular membranes, which might influence the localization or function of transmembrane proteins.

Nystatin

1400-61-9sc-212431
sc-212431A
sc-212431B
sc-212431C
5 MU
25 MU
250 MU
5000 MU
$51.00
$129.00
$251.00
$3570.00
7
(1)

Another compound that binds to cholesterol in cellular membranes, affecting lipid rafts and potentially influencing transmembrane proteins.

Amiloride • HCl

2016-88-8sc-3578
sc-3578A
25 mg
100 mg
$22.00
$57.00
6
(2)

Known to inhibit certain sodium channels, it could potentially influence transmembrane ion gradients and proteins.

Chlorpromazine

50-53-3sc-357313
sc-357313A
5 g
25 g
$61.00
$110.00
21
(1)

A cationic amphiphilic drug that can interfere with cellular membranes and potentially affect transmembrane protein functions.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

A tyrosine kinase inhibitor that might influence cell signaling and thus the function or expression of certain transmembrane proteins.

Emetine

483-18-1sc-470668
sc-470668A
sc-470668B
sc-470668C
1 mg
10 mg
50 mg
100 mg
$440.00
$900.00
$1400.00
$2502.00
(0)

Like cycloheximide, emetine inhibits protein synthesis and could reduce the expression of various proteins, including TMEM34.

Capsazepine

138977-28-3sc-201098
sc-201098A
5 mg
25 mg
$148.00
$459.00
11
(1)

Known to inhibit certain transmembrane ion channels, it might influence the function or expression of related transmembrane proteins.