Date published: 2025-9-10

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TMEM207 Inhibitors

Transmembrane protein 207 (TMEM207) is an integral membrane protein that, as its name implies, resides within the lipid bilayer of cells. It is characterized by its ability to span across the membrane, typically with one or more hydrophobic domains anchoring it in place. The specific functions of TMEM207 are not as well characterized as those of many other transmembrane proteins, but it has been implicated in various cellular processes based on its localization and interaction with other cellular components.

TMEM207 has been of interest in oncology research due to its overexpression in certain types of cancer cells, suggesting a potential role in tumorigenesis or cancer progression. This protein has been associated with the malignant transformation of cells and has been proposed as a biomarker for certain cancer types. The expression of TMEM207 is believed to influence the behavior of cancer cells, possibly affecting their invasiveness and ability to metastasize.On a molecular level, TMEM207 may interact with other proteins within the cell membrane to modulate signaling pathways that control cell growth, cell differentiation, or apoptosis. Its transmembrane nature suggests that it could play a role in the transmission of signals from the extracellular environment to the cell's interior, which is a key aspect of how cells respond to external stimuli.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Inhibits eukaryotic protein synthesis, potentially reducing TMEM207 expression at the translational level.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Binds to DNA and prevents transcription; could suppress TMEM207 mRNA synthesis.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Inhibitor of mTOR, may decrease protein synthesis including TMEM207 by affecting translation initiation.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor, potentially reducing methylation-mediated silencing of TMEM207.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

May inhibit transcription factors and reduce TMEM207 mRNA levels.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

Proteasome inhibitor, could increase cellular stress, leading to reduced TMEM207 expression.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Lysosomotropic agent, might disrupt organelle function indirectly affecting TMEM207 expression.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$30.00
$52.00
$122.00
$367.00
25
(3)

Disrupts ER to Golgi transport, possibly impacting TMEM207 localization and stability.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$169.00
$299.00
66
(3)

Induces ER stress and could lead to decreased expression of membrane proteins like TMEM207.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Modulates gene expression and could downregulate TMEM207 transcription.