Date published: 2026-2-3

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TLR CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. TLR gene silencers are available as TLR CRISPR/Cas9 Knockout plasmids and TLR Double Nickase Plasmids. TLR CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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TLR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLR1 CRISPR/Cas9 KO Plasmid (h)

sc-402458hGene KnockoutGFP0
(0)

TLR1 HDR Plasmid (h)

sc-402458-HDRhHomology Directed RepairPuromycin0
(0)

TLR2 CRISPR/Cas9 KO Plasmid (h)

sc-400267hGene KnockoutGFP0
(4)

TLR2 HDR Plasmid (h)

sc-400267-HDRhHomology Directed RepairPuromycin0
(4)

TLR2 Double Nickase Plasmid (h)

sc-400267-NIChGene KnockoutPuromycin0
(4)

TLR2 Double Nickase Plasmid (h2)

sc-400267-NIC-2hGene KnockoutPuromycin0
(4)

TLR2 CRISPR/Cas9 KO Plasmid (m)

sc-423981mGene KnockoutGFP0
(0)

TLR2 HDR Plasmid (m)

sc-423981-HDRmHomology Directed RepairPuromycin0
(0)

TLR3 CRISPR/Cas9 KO Plasmid (h)

sc-400512hGene KnockoutGFP
1
(0)

TLR3 HDR Plasmid (h)

sc-400512-HDRhHomology Directed RepairPuromycin
1
(0)

TLR3 Double Nickase Plasmid (h)

sc-400512-NIChGene KnockoutPuromycin
1
(0)

TLR3 Double Nickase Plasmid (h2)

sc-400512-NIC-2hGene KnockoutPuromycin
1
(0)

TLR3 CRISPR/Cas9 KO Plasmid (m)

sc-431258mGene KnockoutGFP0
(0)

TLR3 HDR Plasmid (m)

sc-431258-HDRmHomology Directed RepairPuromycin0
(0)

TLR3 Double Nickase Plasmid (m)

sc-431258-NICmGene KnockoutPuromycin0
(0)

TLR3 Double Nickase Plasmid (m2)

sc-431258-NIC-2mGene KnockoutPuromycin0
(0)

TLR4 CRISPR/Cas9 KO Plasmid (h2)

sc-400068-KO-2hGene KnockoutGFP
2
(0)

TLR4 Double Nickase Plasmid (h)

sc-400068-NIChGene KnockoutPuromycin
2
(0)

TLR4 Double Nickase Plasmid (h2)

sc-400068-NIC-2hGene KnockoutPuromycin
2
(0)

TLR4 CRISPR/Cas9 KO Plasmid (m)

sc-423419mGene KnockoutGFP
3
(0)

TLR4 HDR Plasmid (m)

sc-423419-HDRmHomology Directed RepairPuromycin
3
(0)

TLR4 Double Nickase Plasmid (m)

sc-423419-NICmGene KnockoutPuromycin
3
(0)

TLR5 CRISPR/Cas9 KO Plasmid (h)

sc-401154hGene KnockoutGFP0
(0)

TLR5 HDR Plasmid (h)

sc-401154-HDRhHomology Directed RepairPuromycin0
(0)

TLR5 Double Nickase Plasmid (h)

sc-401154-NIChGene KnockoutPuromycin0
(0)

TLR5 Double Nickase Plasmid (h2)

sc-401154-NIC-2hGene KnockoutPuromycin0
(0)

TLR5 CRISPR/Cas9 KO Plasmid (m)

sc-424744mGene KnockoutGFP0
(0)

TLR5 HDR Plasmid (m)

sc-424744-HDRmHomology Directed RepairPuromycin0
(0)

TLR6 CRISPR/Cas9 KO Plasmid (h)

sc-401996hGene KnockoutGFP0
(0)

TLR6 CRISPR/Cas9 KO Plasmid (m)

sc-423420mGene KnockoutGFP0
(0)

TLR7 CRISPR/Cas9 KO Plasmid (h)

sc-401189hGene KnockoutGFP0
(0)

TLR7 HDR Plasmid (h)

sc-401189-HDRhHomology Directed RepairPuromycin0
(0)

TLR7 CRISPR/Cas9 KO Plasmid (m)

sc-431302mGene KnockoutGFP0
(0)

TLR7 Double Nickase Plasmid (m)

sc-431302-NICmGene KnockoutPuromycin0
(0)

TLR7 Double Nickase Plasmid (m2)

sc-431302-NIC-2mGene KnockoutPuromycin0
(0)

TLR8 CRISPR/Cas9 KO Plasmid (h)

sc-401721hGene KnockoutGFP0
(0)

TLR8 HDR Plasmid (h)

sc-401721-HDRhHomology Directed RepairPuromycin0
(0)

TLR8 CRISPR/Cas9 KO Plasmid (m)

sc-431303mGene KnockoutGFP0
(0)

TLR9 CRISPR/Cas9 KO Plasmid (h)

sc-400600hGene KnockoutGFP
1
(0)

TLR9 HDR Plasmid (h)

sc-400600-HDRhHomology Directed RepairPuromycin
1
(0)

TLR9 Double Nickase Plasmid (h)

sc-400600-NIChGene KnockoutPuromycin
1
(0)

TLR9 Double Nickase Plasmid (h2)

sc-400600-NIC-2hGene KnockoutPuromycin
1
(0)

TLR9 Double Nickase Plasmid (m)

sc-429882-NICmGene KnockoutPuromycin0
(0)

TLR9 Double Nickase Plasmid (m2)

sc-429882-NIC-2mGene KnockoutPuromycin0
(0)

TLR10 CRISPR/Cas9 KO Plasmid (h)

sc-417730hGene KnockoutGFP0
(0)

TLR10 HDR Plasmid (h)

sc-417730-HDRhHomology Directed RepairPuromycin0
(0)

TLR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLR1 CRISPR Activation Plasmid (h)

sc-402458-ACThGene ActivationPuro, Blast, Hygro0
(0)

TLR1 CRISPR Activation Plasmid (h2)

sc-402458-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TLR2 CRISPR Activation Plasmid (h)

sc-400267-ACThGene ActivationPuro, Blast, Hygro0
(4)

TLR2 CRISPR Activation Plasmid (h2)

sc-400267-ACT-2hGene ActivationPuro, Blast, Hygro0
(4)

TLR3 CRISPR Activation Plasmid (h)

sc-400512-ACThGene ActivationPuro, Blast, Hygro
1
(0)

TLR3 CRISPR Activation Plasmid (h2)

sc-400512-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

TLR3 Lentiviral Activation Particles (h2)

sc-400512-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

TLR4 CRISPR Activation Plasmid (h)

sc-400068-ACThGene ActivationPuro, Blast, Hygro
2
(0)

TLR4 CRISPR Activation Plasmid (h2)

sc-400068-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

TLR4 Lentiviral Activation Particles (h)

sc-400068-LAChGene ActivationPuro, Blast, Hygro
2
(0)

TLR4 CRISPR Activation Plasmid (m)

sc-423419-ACTmGene ActivationPuro, Blast, Hygro
3
(0)

TLR5 CRISPR Activation Plasmid (h)

sc-401154-ACThGene ActivationPuro, Blast, Hygro0
(0)

TLR6 CRISPR Activation Plasmid (h)

sc-401996-ACThGene ActivationPuro, Blast, Hygro0
(0)

TLR7 CRISPR Activation Plasmid (h)

sc-401189-ACThGene ActivationPuro, Blast, Hygro0
(0)

TLR7 CRISPR Activation Plasmid (h2)

sc-401189-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TLR8 CRISPR Activation Plasmid (h)

sc-401721-ACThGene ActivationPuro, Blast, Hygro0
(0)

TLR8 CRISPR Activation Plasmid (h2)

sc-401721-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TLR9 CRISPR Activation Plasmid (h)

sc-400600-ACThGene ActivationPuro, Blast, Hygro
1
(0)

TLR9 CRISPR Activation Plasmid (h2)

sc-400600-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)