Date published: 2026-8-9

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TLR CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. TLR gene silencers are available as TLR CRISPR/Cas9 Knockout plasmids and TLR Double Nickase Plasmids. TLR CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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TLR CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TLR2 CRISPR/Cas9 KO Plasmid (h)

sc-400267Gene Knockouth0
(3)

TLR3 CRISPR/Cas9 KO Plasmid (h)

sc-400512Gene Knockouth0
(0)

TLR9 CRISPR/Cas9 KO Plasmid (h)

sc-400600Gene Knockouth0
(0)

TLR5 CRISPR/Cas9 KO Plasmid (h)

sc-401154Gene Knockouth0
(0)

TLR7 CRISPR/Cas9 KO Plasmid (h)

sc-401189Gene Knockouth0
(0)

TLR8 CRISPR/Cas9 KO Plasmid (h)

sc-401721Gene Knockouth0
(0)

TLR6 CRISPR/Cas9 KO Plasmid (h)

sc-401996Gene Knockouth0
(0)

TLR1 CRISPR/Cas9 KO Plasmid (h)

sc-402458Gene Knockouth0
(0)

TLR10 CRISPR/Cas9 KO Plasmid (h)

sc-417730Gene Knockouth0
(0)

TLR4 CRISPR/Cas9 KO Plasmid (m)

sc-423419Gene Knockoutm0
(0)

TLR6 CRISPR/Cas9 KO Plasmid (m)

sc-423420Gene Knockoutm0
(0)

TLR2 CRISPR/Cas9 KO Plasmid (m)

sc-423981Gene Knockoutm0
(0)

TLR5 CRISPR/Cas9 KO Plasmid (m)

sc-424744Gene Knockoutm0
(0)

TLR3 CRISPR/Cas9 KO Plasmid (m)

sc-431258Gene Knockoutm0
(0)

TLR7 CRISPR/Cas9 KO Plasmid (m)

sc-431302Gene Knockoutm0
(0)

TLR8 CRISPR/Cas9 KO Plasmid (m)

sc-431303Gene Knockoutm0
(0)

TLR2 HDR Plasmid (h)

sc-400267-HDRHomology Directed Repairh0
(3)

TLR3 HDR Plasmid (h)

sc-400512-HDRHomology Directed Repairh0
(0)

TLR9 HDR Plasmid (h)

sc-400600-HDRHomology Directed Repairh0
(0)

TLR5 HDR Plasmid (h)

sc-401154-HDRHomology Directed Repairh0
(0)

TLR7 HDR Plasmid (h)

sc-401189-HDRHomology Directed Repairh0
(0)

TLR8 HDR Plasmid (h)

sc-401721-HDRHomology Directed Repairh0
(0)

TLR1 HDR Plasmid (h)

sc-402458-HDRHomology Directed Repairh0
(0)

TLR10 HDR Plasmid (h)

sc-417730-HDRHomology Directed Repairh0
(0)

TLR4 HDR Plasmid (m)

sc-423419-HDRHomology Directed Repairm0
(0)

TLR2 HDR Plasmid (m)

sc-423981-HDRHomology Directed Repairm0
(0)

TLR5 HDR Plasmid (m)

sc-424744-HDRHomology Directed Repairm0
(0)

TLR3 HDR Plasmid (m)

sc-431258-HDRHomology Directed Repairm0
(0)

TLR4 CRISPR/Cas9 KO Plasmid (h2)

sc-400068-KO-2Gene Knockouth0
(0)

TLR4 HDR Plasmid (h2)

sc-400068-HDR-2Homology Directed Repairh0
(0)

TLR CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TLR4 Double Nickase Plasmid (h)

sc-400068-NICGene Knockouth0
(0)

TLR2 Double Nickase Plasmid (h)

sc-400267-NICGene Knockouth0
(0)

TLR3 Double Nickase Plasmid (h)

sc-400512-NICGene Knockouth0
(0)

TLR9 Double Nickase Plasmid (h)

sc-400600-NICGene Knockouth0
(0)

TLR5 Double Nickase Plasmid (h)

sc-401154-NICGene Knockouth0
(0)

TLR4 Double Nickase Plasmid (m)

sc-423419-NICGene Knockoutm0
(0)

TLR9 Double Nickase Plasmid (m)

sc-429882-NICGene Knockoutm0
(0)

TLR3 Double Nickase Plasmid (m)

sc-431258-NICGene Knockoutm0
(0)

TLR7 Double Nickase Plasmid (m)

sc-431302-NICGene Knockoutm0
(0)

TLR4 Double Nickase Plasmid (h2)

sc-400068-NIC-2Gene Knockouth0
(0)

TLR2 Double Nickase Plasmid (h2)

sc-400267-NIC-2Gene Knockouth0
(0)

TLR3 Double Nickase Plasmid (h2)

sc-400512-NIC-2Gene Knockouth0
(0)

TLR9 Double Nickase Plasmid (h2)

sc-400600-NIC-2Gene Knockouth0
(0)

TLR5 Double Nickase Plasmid (h2)

sc-401154-NIC-2Gene Knockouth0
(0)

TLR9 Double Nickase Plasmid (m2)

sc-429882-NIC-2Gene Knockoutm0
(0)

TLR3 Double Nickase Plasmid (m2)

sc-431258-NIC-2Gene Knockoutm0
(0)

TLR7 Double Nickase Plasmid (m2)

sc-431302-NIC-2Gene Knockoutm0
(0)

TLR CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TLR4 CRISPR Activation Plasmid (h)

sc-400068-ACTGene Activationh0
(0)

TLR2 CRISPR Activation Plasmid (h)

sc-400267-ACTGene Activationh0
(0)

TLR3 CRISPR Activation Plasmid (h)

sc-400512-ACTGene Activationh0
(0)

TLR9 CRISPR Activation Plasmid (h)

sc-400600-ACTGene Activationh0
(0)

TLR5 CRISPR Activation Plasmid (h)

sc-401154-ACTGene Activationh0
(0)

TLR7 CRISPR Activation Plasmid (h)

sc-401189-ACTGene Activationh0
(0)

TLR8 CRISPR Activation Plasmid (h)

sc-401721-ACTGene Activationh0
(0)

TLR6 CRISPR Activation Plasmid (h)

sc-401996-ACTGene Activationh0
(0)

TLR1 CRISPR Activation Plasmid (h)

sc-402458-ACTGene Activationh0
(0)

TLR4 CRISPR Activation Plasmid (m)

sc-423419-ACTGene Activationm0
(0)

TLR4 CRISPR Activation Plasmid (h2)

sc-400068-ACT-2Gene Activationh0
(0)

TLR2 CRISPR Activation Plasmid (h2)

sc-400267-ACT-2Gene Activationh0
(0)

TLR3 CRISPR Activation Plasmid (h2)

sc-400512-ACT-2Gene Activationh0
(0)

TLR9 CRISPR Activation Plasmid (h2)

sc-400600-ACT-2Gene Activationh0
(0)

TLR7 CRISPR Activation Plasmid (h2)

sc-401189-ACT-2Gene Activationh0
(0)

TLR8 CRISPR Activation Plasmid (h2)

sc-401721-ACT-2Gene Activationh0
(0)

TLR1 CRISPR Activation Plasmid (h2)

sc-402458-ACT-2Gene Activationh0
(0)

TLR4 Lentiviral Activation Particles (h)

sc-400068-LACGene Activationh0
(0)

TLR3 Lentiviral Activation Particles (h2)

sc-400512-LAC-2Gene Activationh0
(0)