Date published: 2026-4-25

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TLK1 Antibodies

Santa Cruz Biotechnology provides a broad selection of TLK1 monoclonal antibodies for research focused on understanding TLK1 protein functions. The monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TLK1, or Tousled-like kinase 1, is a serine/threonine kinase that plays a critical role in DNA damage response and cell cycle regulation. TLK1 is essential for proper chromatin remodeling and is involved in the phosphorylation of histone proteins, which is crucial for DNA replication and repair processes. Research has shown that TLK1 activity influences cellular responses to DNA damage and stress conditions. Understanding TLK1 function has significant implications for cancer research, as altered TLK1 expression levels have been observed in various cancer types. TLK1 research continues to reveal new insights into cell cycle control and DNA repair mechanisms. Ongoing studies of TLK1 are uncovering potential therapeutic applications in cancer treatment. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of TLK1's role in cellular processes and disease development.

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TLK1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TLK1 Antibody (G-8)

sc-393515mouse IgG2a κ126-161 (h)WB, IP, IF, ELISAm, r, h

new

(1)

TLK1 Antibody (S-32)

sc-100345mouse IgG3 κ111-230 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(2)

TLK1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLK1 CRISPR/Cas9 KO Plasmid (h)

sc-407634hGene KnockoutGFP0
(0)

TLK1 HDR Plasmid (h)

sc-407634-HDRhHomology Directed RepairPuromycin0
(0)

TLK1 Double Nickase Plasmid (h)

sc-407634-NIChGene KnockoutPuromycin0
(0)

TLK1 Double Nickase Plasmid (h2)

sc-407634-NIC-2hGene KnockoutPuromycin0
(0)

TLK1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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TLK1 siRNA (h)

sc-45973hGene SilencingN/A0
(0)

TLK1 shRNA Plasmid (h)

sc-45973-SHhGene SilencingPuromycin0
(0)

TLK1 shRNA (h) Lentiviral Particles

sc-45973-VhGene SilencingPuromycin0
(0)

TLK1 siRNA (m)

sc-45974mGene SilencingN/A0
(0)

TLK1 shRNA Plasmid (m)

sc-45974-SHmGene SilencingPuromycin0
(0)

TLK1 shRNA (m) Lentiviral Particles

sc-45974-VmGene SilencingPuromycin0
(0)