Date published: 2026-5-6

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TIMP-1 Activators

Common TIMP-1 Activators include, but are not limited to Angiotensin II, Human CAS 4474-91-3, PGE2 CAS 363-24-6, Curcumin CAS 458-37-7, (-)-Epigallocatechin Gallate CAS 989-51-5 and Quercetin CAS 117-39-5.

TIMP-1 Activators constitute a distinctive category of chemical compounds known for their capability to modulate the activity of tissue inhibitor of metalloproteinase-1 (TIMP-1). This chemical class operates by interacting with and enhancing the signaling pathways associated with TIMP-1, a member of the TIMP family that plays a critical role in regulating extracellular matrix remodeling and tissue homeostasis. TIMP-1 is recognized for its involvement in various biological processes, including cell migration, tissue repair, and maintenance of tissue structure.

TIMP-1 Activators exert their influence through specific molecular interactions that could amplify the downstream effects of TIMP-1-mediated signaling, contributing to the fine-tuning of extracellular matrix turnover, cell adhesion, and tissue integrity. The intricate mechanisms through which TIMP-1 Activators impact TIMP-1-related pathways are subjects of ongoing scientific exploration, providing insights into the complex interplay between cellular communication and tissue architecture. The specific ways in which this chemical class engages with TIMP-1 highlight its significance in unraveling the intricacies of extracellular matrix regulation and enhancing our understanding across various scientific domains.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Angiotensin II, Human

4474-91-3sc-363643
sc-363643A
sc-363643B
sc-363643C
1 mg
5 mg
25 mg
100 mg
$51.00
$100.00
$310.00
$690.00
3
(1)

A hormone regulating blood pressure and fluid balance, it induces TIMP-1 expression for vascular remodeling and tissue repair.

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$57.00
$159.00
$275.00
$678.00
37
(1)

A lipid signaling molecule with effects on inflammation and cell behavior, it upregulates TIMP-1 expression for tissue repair and ECM maintenance.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

A natural compound with anti-inflammatory and antioxidant properties, it induces TIMP-1 expression, potentially impacting tissue protection and ECM balance.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A polyphenol known for potential health benefits, it induces TIMP-1 expression, potentially influencing ECM remodeling and aging-related processes.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A major green tea polyphenol with antioxidants, it induces TIMP-1 expression, aiding in ECM maintenance and potential anti-aging effects.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

A flavonoid found in fruits and vegetables, it associates with TIMP-1 expression, potentially influencing ECM remodeling.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

With diverse effects including immune modulation and tissue regulation, it induces TIMP-1 expression for tissue repair and ECM integrity.