TGIF2LX Activators
TGIF2LX, or TGFB-Induced Factor Homeobox 2-Like, X-Linked, is a protein encoded by the TGIF2LX gene located on the X chromosome. While specific details about the function of TGIF2LX are not as extensively characterized as some other proteins, it is known to belong to the three-amino acid loop extension (TALE) superclass of atypical homeobox genes. Proteins in this category are known to play roles in development, cell differentiation, and regulation of gene expression.The TGIF2LX protein is expected to function as a transcriptional regulator due to its homeobox domain, which enables it to bind DNA and influence the transcription of target genes. Homeobox genes are critical in the early stages of embryonic development, and their precise regulation is necessary for the correct formation of body plans and organ systems. The atypical structure of the TALE superclass suggests that TGIF2LX may have specialized roles in transcriptional regulation.
Given its X-linked nature, TGIF2LX may have implications for sex-specific phenotypes and disorders. In many species, genes on the X chromosome can escape X-inactivation, a process that silences one of the two X chromosomes in females, which can lead to differences in gene expression between males and females. This could potentially make TGIF2LX relevant in understanding certain sex-linked genetic conditions.Research into TGIF2LX may involve exploring its expression patterns in various tissues, identifying its target genes, and understanding how it interacts with other transcription factors and cofactors. These studies can help clarify its role in cell biology and development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thymosin β4 | 77591-33-4 | sc-396076 sc-396076A | 1 mg 100 mg | $134.00 $7140.00 | ||
As TGIF2LX is related to TGF-β signaling, TGF-β1 can potentially influence its activity by activating this pathway. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
A TGF-β receptor inhibitor, potentially affecting TGIF2LX activity by altering TGF-β signaling pathways. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
BMP inhibitor, could influence TGIF2LX activity by modulating the BMP signaling pathway, which is related to TGF-β signaling. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
TGF-β receptor kinase inhibitor, might indirectly affect TGIF2LX activity by inhibiting TGF-β signaling. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
Selective inhibitor of TGF-β type I receptor ALK5 kinase, potentially affecting TGIF2LX through TGF-β signaling modulation. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
BMP type I receptor kinase inhibitor, might influence TGIF2LX activity through BMP/TGF-β signaling pathways. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
Inhibitor of TGF-β type I receptor ALK5, potentially influencing TGIF2LX activity by modulating TGF-β signaling. | ||||||
LY2157299 | 700874-72-2 | sc-391123 sc-391123A | 5 mg 10 mg | $213.00 $359.00 | 3 | |
TGF-β receptor kinase inhibitor, could affect TGIF2LX activity through TGF-β signaling modulation. | ||||||
GSK 2606414 | 1337531-36-8 | sc-490182 sc-490182A | 5 mg 25 mg | $163.00 $572.00 | ||
A potent inhibitor of TGF-β signaling, potentially affecting TGIF2LX activity. | ||||||
Pirfenidone | 53179-13-8 | sc-203663 sc-203663A | 10 mg 50 mg | $102.00 $416.00 | 6 | |
Inhibits TGF-β synthesis and TGF-β induced collagen synthesis, potentially impacting TGIF2LX activity. | ||||||