Date published: 2025-11-24

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SYP Activators

Common SYP Activators include, but are not limited to Retinoic Acid, all trans CAS 302-79-4, Potassium Chloride CAS 7447-40-7, Valproic Acid CAS 99-66-1, Calcium dibutyryladenosine cyclophosphate CAS 362-74-3 and Forskolin CAS 66575-29-9.

Synaptophysin (SYP) is a membrane glycoprotein of synaptic vesicles present in neurons and is often used as a marker for neuroendocrine cells and neoplasms. The regulation of SYP expression can be influenced by various factors, including chemical compounds that modulate neuronal activity or differentiation. SYP Activators are a class of compounds or molecules that impact the activity or function of Synaptophysin (SYP). Synaptophysin is a critical protein primarily found in neurons, particularly in synaptic vesicles. These vesicles are small membrane-bound sacs that store and release neurotransmitters, which are essential for transmitting signals between nerve cells. Synaptophysin plays a pivotal role in synaptic vesicle trafficking, fusion, and neurotransmitter release, making it crucial for proper neuronal communication.

Activation of Synaptophysin can involve various mechanisms, such as changes in its conformation or interactions with other proteins. SYP Activators may modulate these functions, influencing the efficiency of neurotransmitter release and synaptic communication. While the practical applications of these activators may not be immediately apparent, understanding their effects on Synaptophysin can provide valuable insights into the intricate processes underlying neuronal function. This knowledge contributes to our broader understanding of neurobiology, potentially paving the way for future research in neuroscience and neurodegenerative disorders where dysregulation of synaptic function may be implicated.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Influences neuronal differentiation and might upregulate SYP expression in certain contexts.

Potassium Chloride

7447-40-7sc-203207
sc-203207A
sc-203207B
sc-203207C
500 g
2 kg
5 kg
10 kg
$25.00
$56.00
$104.00
$183.00
5
(1)

Depolarizing agent that can activate neurons, potentially leading to increased SYP expression.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

A histone deacetylase inhibitor used as an anticonvulsant; it might influence SYP expression in neurons.

Calcium dibutyryladenosine cyclophosphate

362-74-3sc-482205
25 mg
$147.00
(0)

Elevates intracellular cAMP and can promote neuronal differentiation, possibly influencing SYP expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Activates adenylate cyclase, increasing cAMP levels, which might influence neuronal differentiation and SYP expression.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

Activates protein kinase C, potentially influencing neuronal activity and SYP expression.

GABA

56-12-2sc-203053
sc-203053A
sc-203053B
sc-203053C
10 g
25 g
5 kg
10 kg
$63.00
$133.00
$450.00
$750.00
2
(1)

Major inhibitory neurotransmitter in the brain; its role in direct modulation of SYP expression is less clear.

L-Glutamic Acid

56-86-0sc-394004
sc-394004A
10 g
100 g
$291.00
$566.00
(0)

Major excitatory neurotransmitter in the brain; might influence SYP expression through neuronal activation.

Lamotrigine

84057-84-1sc-201079
sc-201079A
10 mg
50 mg
$118.00
$476.00
1
(1)

An anticonvulsant that modulates voltage-sensitive sodium channels; might influence SYP expression in certain contexts.