Synaptophysin (SYP) is a membrane glycoprotein of synaptic vesicles present in neurons and is often used as a marker for neuroendocrine cells and neoplasms. The regulation of SYP expression can be influenced by various factors, including chemical compounds that modulate neuronal activity or differentiation. SYP Activators are a class of compounds or molecules that impact the activity or function of Synaptophysin (SYP). Synaptophysin is a critical protein primarily found in neurons, particularly in synaptic vesicles. These vesicles are small membrane-bound sacs that store and release neurotransmitters, which are essential for transmitting signals between nerve cells. Synaptophysin plays a pivotal role in synaptic vesicle trafficking, fusion, and neurotransmitter release, making it crucial for proper neuronal communication.
Activation of Synaptophysin can involve various mechanisms, such as changes in its conformation or interactions with other proteins. SYP Activators may modulate these functions, influencing the efficiency of neurotransmitter release and synaptic communication. While the practical applications of these activators may not be immediately apparent, understanding their effects on Synaptophysin can provide valuable insights into the intricate processes underlying neuronal function. This knowledge contributes to our broader understanding of neurobiology, potentially paving the way for future research in neuroscience and neurodegenerative disorders where dysregulation of synaptic function may be implicated.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences neuronal differentiation and might upregulate SYP expression in certain contexts. | ||||||
Potassium Chloride | 7447-40-7 | sc-203207 sc-203207A sc-203207B sc-203207C | 500 g 2 kg 5 kg 10 kg | $25.00 $56.00 $104.00 $183.00 | 5 | |
Depolarizing agent that can activate neurons, potentially leading to increased SYP expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
A histone deacetylase inhibitor used as an anticonvulsant; it might influence SYP expression in neurons. | ||||||
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
Elevates intracellular cAMP and can promote neuronal differentiation, possibly influencing SYP expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which might influence neuronal differentiation and SYP expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C, potentially influencing neuronal activity and SYP expression. | ||||||
GABA | 56-12-2 | sc-203053 sc-203053A sc-203053B sc-203053C | 10 g 25 g 5 kg 10 kg | $63.00 $133.00 $450.00 $750.00 | 2 | |
Major inhibitory neurotransmitter in the brain; its role in direct modulation of SYP expression is less clear. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
Major excitatory neurotransmitter in the brain; might influence SYP expression through neuronal activation. | ||||||
Lamotrigine | 84057-84-1 | sc-201079 sc-201079A | 10 mg 50 mg | $118.00 $476.00 | 1 | |
An anticonvulsant that modulates voltage-sensitive sodium channels; might influence SYP expression in certain contexts. | ||||||