Date published: 2026-1-9

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Syne CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Syne gene silencers are available as Syne CRISPR/Cas9 Knockout plasmids and Syne Double Nickase Plasmids. Syne CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Syne CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Syne-1 CRISPR/Cas9 KO Plasmid (h)

sc-402804hGene KnockoutGFP0
(0)

Syne-1 CRISPR/Cas9 KO Plasmid (h2)

sc-402804-KO-2hGene KnockoutGFP0
(0)

Syne-1 HDR Plasmid (h2)

sc-402804-HDR-2hHomology Directed RepairPuromycin0
(0)

Syne-1 Double Nickase Plasmid (h)

sc-402804-NIChGene KnockoutPuromycin0
(0)

Syne-1 Double Nickase Plasmid (h2)

sc-402804-NIC-2hGene KnockoutPuromycin0
(0)

Syne-1 CRISPR/Cas9 KO Plasmid (m)

sc-425661mGene KnockoutGFP0
(0)

Syne-1 HDR Plasmid (m)

sc-425661-HDRmHomology Directed RepairPuromycin0
(0)

Syne-1 Double Nickase Plasmid (m)

sc-425661-NICmGene KnockoutPuromycin0
(0)

Syne-1 Double Nickase Plasmid (m2)

sc-425661-NIC-2mGene KnockoutPuromycin0
(0)

Syne-2 CRISPR/Cas9 KO Plasmid (h)

sc-403318hGene KnockoutGFP0
(0)

Syne-2 HDR Plasmid (h)

sc-403318-HDRhHomology Directed RepairPuromycin0
(0)

Syne-2 Double Nickase Plasmid (h)

sc-403318-NIChGene KnockoutPuromycin0
(0)

Syne-2 Double Nickase Plasmid (h2)

sc-403318-NIC-2hGene KnockoutPuromycin0
(0)

Syne-2 CRISPR/Cas9 KO Plasmid (m)

sc-435634mGene KnockoutGFP0
(0)

Syne-2 HDR Plasmid (m)

sc-435634-HDRmHomology Directed RepairPuromycin0
(0)

Syne-2 Double Nickase Plasmid (m)

sc-435634-NICmGene KnockoutPuromycin0
(0)

Syne-2 Double Nickase Plasmid (m2)

sc-435634-NIC-2mGene KnockoutPuromycin0
(0)

Syne-3 CRISPR/Cas9 KO Plasmid (h)

sc-407252hGene KnockoutGFP0
(0)

Syne-3 HDR Plasmid (h)

sc-407252-HDRhHomology Directed RepairPuromycin0
(0)

Syne-3 Double Nickase Plasmid (h2)

sc-407252-NIC-2hGene KnockoutPuromycin0
(0)

C14orf49 Double Nickase Plasmid (h)

sc-407252-NIChGene KnockoutPuromycin0
(0)

C19orf46 CRISPR/Cas9 KO Plasmid (h)

sc-407273hGene KnockoutGFP0
(0)

C19orf46 HDR Plasmid (h)

sc-407273-HDRhHomology Directed RepairPuromycin0
(0)

C19orf46 Double Nickase Plasmid (h)

sc-407273-NIChGene KnockoutPuromycin0
(0)

C19orf46 Double Nickase Plasmid (h2)

sc-407273-NIC-2hGene KnockoutPuromycin0
(0)

Syne CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Syne-1 CRISPR Activation Plasmid (h)

sc-402804-ACThGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 CRISPR Activation Plasmid (h2)

sc-402804-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 Lentiviral Activation Particles (h)

sc-402804-LAChGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 Lentiviral Activation Particles (h2)

sc-402804-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 CRISPR Activation Plasmid (m)

sc-425661-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 CRISPR Activation Plasmid (m2)

sc-425661-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 Lentiviral Activation Particles (m)

sc-425661-LACmGene ActivationPuro, Blast, Hygro0
(0)

Syne-1 Lentiviral Activation Particles (m2)

sc-425661-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 CRISPR Activation Plasmid (h)

sc-403318-ACThGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 CRISPR Activation Plasmid (h2)

sc-403318-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 Lentiviral Activation Particles (h)

sc-403318-LAChGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 Lentiviral Activation Particles (h2)

sc-403318-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 CRISPR Activation Plasmid (m)

sc-435634-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 CRISPR Activation Plasmid (m2)

sc-435634-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 Lentiviral Activation Particles (m)

sc-435634-LACmGene ActivationPuro, Blast, Hygro0
(0)

Syne-2 Lentiviral Activation Particles (m2)

sc-435634-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Syne-3 CRISPR Activation Plasmid (h2)

sc-407252-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Syne-3 Lentiviral Activation Particles (h2)

sc-407252-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

C14orf49 CRISPR Activation Plasmid (h)

sc-407252-ACThGene ActivationPuro, Blast, Hygro0
(0)

C14orf49 Lentiviral Activation Particles (h)

sc-407252-LAChGene ActivationPuro, Blast, Hygro0
(0)

C19orf46 CRISPR Activation Plasmid (h)

sc-407273-ACThGene ActivationPuro, Blast, Hygro0
(0)

C19orf46 CRISPR Activation Plasmid (h2)

sc-407273-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

C19orf46 Lentiviral Activation Particles (h)

sc-407273-LAChGene ActivationPuro, Blast, Hygro0
(0)

C19orf46 Lentiviral Activation Particles (h2)

sc-407273-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)