Stem Cell Reagents
Items 11 to 20 of 200 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Valproic acid sodium salt | 1069-66-5 | sc-202378A sc-202378 sc-202378B sc-202378C | 1 g 5 g 25 g 100 g | $21.00 $37.00 $131.00 $369.00 | 9 | |
Valproic acid sodium salt serves as a versatile stem cell reagent by modulating epigenetic mechanisms, particularly through the inhibition of histone deacetylases. This action promotes a more open chromatin structure, facilitating gene expression associated with pluripotency and differentiation. Its ability to influence metabolic pathways and enhance cellular plasticity makes it a valuable tool in stem cell research, driving advancements in understanding cellular reprogramming and lineage commitment. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $96.00 $292.00 | 27 | |
IWP-2 is a potent stem cell reagent that selectively inhibits the Wnt signaling pathway, crucial for regulating cell fate decisions. By disrupting the interaction between Wnt ligands and their receptors, IWP-2 effectively alters downstream gene expression, promoting a shift towards pluripotency. Its unique mechanism enhances the efficiency of reprogramming somatic cells into induced pluripotent stem cells, providing insights into cellular dynamics and developmental biology. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $124.00 $502.00 | 13 | |
Garcinol is a versatile stem cell reagent known for its ability to modulate cellular pathways through the inhibition of histone acetyltransferases. This action leads to altered chromatin dynamics, influencing gene expression patterns associated with stem cell maintenance and differentiation. By promoting a more favorable epigenetic landscape, Garcinol enhances the reprogramming efficiency of somatic cells, offering a unique approach to understanding stem cell biology and cellular plasticity. | ||||||
Dorsomorphin dihydrochloride | 1219168-18-9 | sc-361173 sc-361173A | 10 mg 50 mg | $186.00 $751.00 | 28 | |
Dorsomorphin dihydrochloride is a potent stem cell reagent that selectively inhibits AMP-activated protein kinase (AMPK) pathways, impacting cellular metabolism and energy homeostasis. Its unique interaction with the TGF-β signaling cascade modulates stem cell fate decisions, promoting differentiation while suppressing self-renewal. This compound's ability to fine-tune cellular responses through targeted signaling interference provides valuable insights into stem cell regulation and developmental biology. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD 98059 is a selective inhibitor of the MEK/ERK signaling pathway, crucial for regulating cell proliferation and differentiation. By specifically blocking MEK activity, it disrupts the downstream ERK activation, influencing various cellular processes. This compound's unique ability to modulate the balance between stem cell maintenance and differentiation highlights its role in understanding stem cell dynamics and the intricate signaling networks that govern cellular fate. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
Cyclopamine is a potent antagonist of the Hedgehog signaling pathway, primarily affecting the interaction between the Smoothened receptor and its downstream effectors. By inhibiting this pathway, Cyclopamine alters gene expression patterns critical for stem cell fate determination and lineage specification. Its unique mechanism of action provides insights into the regulatory networks that govern stem cell behavior, influencing processes such as self-renewal and differentiation. | ||||||
Sinefungin | 58944-73-3 | sc-203263 sc-203263B sc-203263C sc-203263A | 1 mg 100 mg 1 g 10 mg | $271.00 $5202.00 $40368.00 $704.00 | 4 | |
Sinefungin is a unique compound that acts as a potent inhibitor of S-adenosylhomocysteine hydrolase, impacting methylation processes within cells. By modulating the levels of S-adenosylmethionine, it influences epigenetic regulation and gene expression, which are crucial for stem cell maintenance and differentiation. Its ability to alter cellular signaling pathways and metabolic states makes it a valuable tool for studying stem cell dynamics and developmental biology. | ||||||
EX 527 | 49843-98-3 | sc-203044 | 5 mg | $87.00 | 32 | |
EX 527 is a selective inhibitor of sirtuin 1, a key regulator of cellular metabolism and aging. By disrupting the deacetylation of target proteins, it influences various signaling pathways, including those involved in stem cell pluripotency and differentiation. Its unique interaction with sirtuin 1 alters the acetylation status of histones and non-histone proteins, thereby affecting gene expression and cellular fate decisions. This compound serves as a critical reagent for exploring stem cell biology and epigenetic mechanisms. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 is a bioactive lipid that plays a pivotal role in modulating stem cell behavior through its interaction with specific receptors, notably EP receptors. It activates distinct signaling pathways, such as the cAMP/PKA pathway, which influences cell proliferation and differentiation. By regulating the balance of pro-inflammatory and anti-inflammatory signals, PGE2 impacts the stem cell niche, promoting self-renewal and lineage commitment. Its dynamic role in cellular communication makes it a vital reagent in stem cell research. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is a nucleotide analog that influences stem cell dynamics by modulating AMP-activated protein kinase (AMPK) pathways. Its unique ability to mimic cellular energy states allows it to activate metabolic pathways that enhance cellular proliferation and differentiation. By altering the energy-sensing mechanisms within stem cells, AICAR promotes metabolic reprogramming, thereby impacting stem cell fate decisions and enhancing regenerative potential. Its role in cellular metabolism makes it a significant reagent in stem cell studies. | ||||||