Date published: 2026-4-24

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SSTR5 Activators

SSTR5 Activators are chemical that can indirectly influence SSTR5, a G-protein coupled receptor (GPCR) pivotal to numerous cellular processes. Several identified compounds can modify pathways and processes related to GPCR signaling, thereby having an effect on SSTR5. For instance, Forskolin, a known enhancer of cAMP levels, and Isoproterenol, a β-adrenergic receptor agonist, can influence GPCR signaling, potentially impacting the activity of SSTR5. Other compounds like Salmeterol and PGE2, functioning as a long-acting β2-adrenergic agonist and a prostaglandin respectively, are also capable of modulating various signaling pathways, subsequently affecting SSTR5. Additionally, compounds like Iloprost, a prostacyclin analog, and Rolipram, a PDE4 inhibitor, by influencing GPCR signaling, may also exert an influence on SSTR5 activity.Compounds that affect cellular signaling and metabolism, such as Resveratrol, also hold the capability to affect SSTR5. Similarly, compounds like Rosiglitazone and Pioglitazone, functioning as PPARγ agonists, can modulate the transcription of target genes, possibly having repercussions on SSTR5. Additionally, Capsaicin, identified as a TRPV1 agonist, can modulate ion channel activity, offering another route through which SSTR5 can be indirectly influenced.

Items 1 to 10 of 14 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-817,818

217480-27-8sc-204048
10 mg
$279.00
(0)

L-817,818 demonstrates a unique affinity for somatostatin receptor subtype 5 (SSTR5), engaging in specific hydrogen bonding and hydrophobic interactions that stabilize receptor-ligand complexes. This compound modulates receptor dynamics, leading to altered intracellular signaling cascades. Its reaction kinetics indicate a gradual dissociation rate, allowing for prolonged receptor activation. Additionally, L-817,818's solubility characteristics enhance its distribution in various environments, influencing its biological interactions.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Can increase cAMP levels, possibly influencing GPCR signaling and indirectly affecting SSTR5 activity.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

β-adrenergic receptor agonist, could modulate GPCR signaling pathways, possibly having an indirect effect on SSTR5.

Salmeterol

89365-50-4sc-224277
sc-224277A
10 mg
50 mg
$186.00
$562.00
1
(1)

Long-acting β2-adrenergic agonist, might indirectly impact SSTR5 via modulation of GPCR pathways.

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$57.00
$159.00
$275.00
$678.00
37
(1)

Prostaglandin E2, might affect various signaling pathways and have an indirect impact on SSTR5 activity.

Iloprost

78919-13-8sc-205349
sc-205349A
500 µg
1 mg
$155.00
$269.00
(0)

Prostacyclin analog, could influence GPCR signaling, potentially having an indirect impact on SSTR5.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$77.00
$216.00
18
(1)

PDE4 inhibitor, can increase cAMP levels, possibly impacting GPCR signaling and indirectly SSTR5.

Cilostazol

73963-72-1sc-201182
sc-201182A
10 mg
50 mg
$109.00
$322.00
3
(1)

PDE3 inhibitor, can elevate cAMP levels, potentially influencing GPCR signaling and having an indirect effect on SSTR5.

L-803,087 trifluoroacetate

217480-26-7sc-203619
10 mg
$320.00
1
(0)

A selective SSTR5 antagonist that has been utilized in research research to understand the role of SSTR5 in various physiological processes.

Milrinone

78415-72-2sc-201193
sc-201193A
10 mg
50 mg
$165.00
$697.00
7
(0)

PDE3 inhibitor, might elevate cAMP levels, potentially impacting GPCR signaling and indirectly affecting SSTR5.