Date published: 2025-12-9

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SR-2C Inhibitors

SR-2C inhibitors, also known as serotonin receptor 2C inhibitors, belong to a specific chemical class of compounds that are primarily designed to modulate the activity of the serotonin 2C receptor subtype in the human brain. The serotonin 2C receptor, abbreviated as 5-HT2C receptor, is a member of the G-protein coupled receptor (GPCR) family and is involved in the regulation of various physiological processes, including mood, appetite, and sleep. SR-2C inhibitors are characterized by their ability to selectively bind to and influence the function of these receptors, either by blocking or stimulating their activity, thus altering the downstream signaling pathways. These inhibitors are typically small organic molecules with a structure that allows them to interact with the serotonin 2C receptor in a specific manner. The binding of SR-2C inhibitors to the receptor can lead to diverse pharmacological effects, depending on their mode of action. Some compounds act as antagonists, effectively preventing serotonin or other endogenous ligands from binding to the receptor, thereby reducing its activation. Others may function as agonists, mimicking the effects of serotonin and activating the receptor. The modulation of 5-HT2C receptor activity by these inhibitors can have profound effects on the brain's neurotransmitter systems, leading to alterations in mood, appetite, and other behaviors. Consequently, SR-2C inhibitors represent a class of compounds that are of interest to researchers studying the neurobiology of mood and appetite regulation

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Arbidol Hydrochloride

131707-23-8sc-210834
10 mg
$204.00
(1)

Arbidol Hydrochloride disrupts viral entry by inhibiting the fusion of the viral envelope with the host cell membrane in SARS-CoV-2.

Dimebolin dihydrochloride

97657-92-6sc-294348
sc-294348A
sc-294348B
1 mg
5 mg
50 mg
$37.00
$96.00
$384.00
(0)

Dimebolin dihydrochloride, an SR-2C compound, exhibits intriguing reactivity stemming from its unique structural features. The presence of halide substituents enhances its electrophilicity, enabling swift acylation and substitution reactions. Its distinct steric profile influences the selectivity of these reactions, guiding the formation of specific products. Additionally, the compound's strong ionic interactions contribute to its solubility characteristics, affecting its behavior in diverse chemical environments.

Imipramine-d6

65100-45-0sc-207754
2.5 mg
$290.00
(0)

Imipramine-d6, classified as an SR-2C compound, showcases remarkable stability due to its deuterated structure, which alters its vibrational modes and enhances its spectroscopic properties. The presence of deuterium affects hydrogen bonding dynamics, leading to unique interaction patterns in solution. Its distinct electronic configuration facilitates selective reactivity in nucleophilic attacks, while its hydrophobic regions influence solubility and partitioning behavior in various solvents.

Ribavirin

36791-04-5sc-203238
sc-203238A
sc-203238B
10 mg
100 mg
5 g
$62.00
$108.00
$210.00
1
(1)

Ribavirin is a nucleoside analog that interferes with viral RNA synthesis, leading to viral RNA chain termination.

Mianserin hydrochloride

21535-47-7sc-358986
100 mg
$110.00
1
(1)

Mianserin hydrochloride, an SR-2C compound, exhibits intriguing solvation dynamics due to its unique molecular architecture. The presence of halide ions enhances its reactivity, promoting specific interactions with polar solvents. Its conformational flexibility allows for diverse intermolecular interactions, influencing its diffusion rates. Additionally, the compound's electronic distribution contributes to its distinct photophysical properties, making it an interesting subject for studies on molecular behavior in various environments.

Asenapine maleate

65576-45-6sc-361110
sc-361110A
10 mg
50 mg
$145.00
$615.00
(0)

Asenapine maleate, classified as an SR-2C compound, showcases remarkable stereochemical properties that influence its reactivity profile. The compound's dual functional groups facilitate unique hydrogen bonding interactions, enhancing its solubility in various media. Its rigid molecular framework restricts conformational changes, leading to predictable kinetic behavior in reactions. Furthermore, the compound's electron-rich regions contribute to its distinctive electrochemical characteristics, making it a subject of interest in studies of molecular interactions.

Sofosbuvir

1190307-88-0sc-482362
25 mg
$143.00
1
(0)

Sofosbuvir inhibits the SARS-CoV-2 RNA-dependent RNA polymerase, hampering viral RNA replication and transcription.