Date published: 2026-1-22

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SPTLC1 Antibodies

Santa Cruz Biotechnology offers a broad range of SPTLC1 monoclonal antibodies for various research applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SPTLC1, or serine palmitoyltransferase long chain base subunit 1, plays a crucial role in sphingolipid metabolism, which is essential for cell membrane integrity and signaling. Dysregulation of SPTLC1 has been implicated in various diseases, including neurodegenerative disorders and cancer. SPTLC1 functions as a key regulator in cellular processes and metabolic pathways. Understanding SPTLC1 expression patterns and interactions provides valuable insights into disease mechanisms and potential therapeutic targets. Researchers can utilize specific detection methods to examine SPTLC1 localization within cellular compartments. Advanced visualization techniques allow for detailed analysis of SPTLC1 distribution in tissue samples. Multiple conjugation options, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), provide flexibility in experimental design. Santa Cruz Biotechnology monoclonal antibodies for SPTLC1 support researchers worldwide in advancing our understanding of cellular biology and disease mechanisms.

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SPTLC1 Antibodies

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SPTLC1 Antibody (H-1)

sc-374143mouse IgG1 κ174-473 (h)WB, IP, IF, ELISAm, r, h
5
(3)

SPTLC1 Antibody (49)

sc-136076mouse IgG1121-238 (m)WB, IP, IFm, r, h
3
(2)

SPTLC1 CRISPR Knockout, HDR and Double Nickase Plasmids

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SPTLC1 CRISPR/Cas9 KO Plasmid (m)

sc-435265mGene KnockoutGFP0
(0)

SPTLC1 HDR Plasmid (m)

sc-435265-HDRmHomology Directed RepairPuromycin0
(0)

SPTLC1 Double Nickase Plasmid (m)

sc-435265-NICmGene KnockoutPuromycin0
(0)

SPTLC1 Double Nickase Plasmid (m2)

sc-435265-NIC-2mGene KnockoutPuromycin0
(0)

SPTLC1 CRISPR Activation Products

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SPTLC1 CRISPR Activation Plasmid (h)

sc-402829-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPTLC1 CRISPR Activation Plasmid (h2)

sc-402829-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPTLC1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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SPTLC1 siRNA (h)

sc-106561hGene SilencingN/A
1
(0)

SPTLC1 shRNA Plasmid (h)

sc-106561-SHhGene SilencingPuromycin
1
(0)

SPTLC1 shRNA (h) Lentiviral Particles

sc-106561-VhGene SilencingPuromycin
1
(0)

SPTLC1 siRNA (m)

sc-153804mGene SilencingN/A
1
(0)

SPTLC1 shRNA Plasmid (m)

sc-153804-SHmGene SilencingPuromycin
1
(0)

SPTLC1 shRNA (m) Lentiviral Particles

sc-153804-VmGene SilencingPuromycin
1
(0)