Date published: 2025-10-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

SPRR2D Activators

SPRR2D Activators constitute a specific category of chemical compounds that have garnered interest within the field of molecular biology and cellular research. These activators are designed to modulate the activity of the SPRR2D gene, with SPRR2D standing for Small Proline-Rich Protein 2D. This gene is a protein-coding element found in humans, and it belongs to a family of small proline-rich proteins that are known to play various roles in skin and epithelial tissue biology. While the precise biological functions of SPRR2D are still under investigation, it is believed to be involved in processes related to the formation and maintenance of the skin's barrier function and epithelial differentiation. SPRR2D Activators represent a group of molecules engineered to enhance or stimulate the expression and function of the SPRR2D gene, ultimately leading to an increase in the activity of the associated protein.

The mechanism of action of SPRR2D Activators generally involves their interaction with specific regulatory elements within the SPRR2D gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the SPRR2D protein. The SPRR2D protein is thought to contribute to the structural integrity of the skin and epithelial tissues by forming cross-links with other proteins, potentially influencing the barrier function and protective properties of these tissues. As scientists continue to investigate the functions and potential implications of SPRR2D activation, the development and refinement of SPRR2D Activators offer the prospect of advancing our understanding of skin biology, epithelial tissue development, and the broader role of SPRR2D in tissue structure and function, potentially uncovering novel aspects of skin and epithelial biology.

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

May upregulate SPRR2D by promoting keratinocyte differentiation and enhancing skin barrier function.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Could stimulate SPRR2D expression in keratinocytes as part of its role in skin health and barrier maintenance.

all-trans Retinal

116-31-4sc-210778A
sc-210778
250 mg
1 g
$126.00
$372.00
7
(2)

As a product of Vitamin A metabolism, all-trans retinal could influence SPRR2D expression in processes of skin renewal and repair.

Hyaluronic acid

9004-61-9sc-337865
10 mg
$204.00
(0)

May enhance SPRR2D expression by promoting skin hydration and contributing to the epidermal barrier function.

Glycolic acid solution

79-14-1sc-215102
sc-215102A
25 g
500 g
$38.00
$60.00
(0)

Glycolic acid could induce SPRR2D expression as part of the keratinocyte response to chemical exfoliation.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$36.00
$102.00
$569.00
$1173.00
10
(1)

As a component of skin's natural oils, oleic acid might influence SPRR2D expression related to barrier function and skin hydration.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$43.00
$65.00
$200.00
$815.00
6
(1)

Known to improve skin barrier function, niacinamide could potentially upregulate SPRR2D in keratinocytes.