Date published: 2026-7-21

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SPRED Antibodies

Santa Cruz Biotechnology features a diverse variety of SPRED Antibodies for advanced research in cellular signaling. SPRED Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SPRED proteins play a crucial role in regulating the Ras signaling pathway, which is essential for cell growth, differentiation, and survival. As negative regulators, SPRED proteins maintain cellular homeostasis and prevent uncontrolled cell proliferation, making them significant in cancer research and other diseases linked to aberrant signaling. Understanding SPRED protein function can provide insights into therapeutic targets for various conditions. Researchers worldwide rely on SPRED monoclonal antibodies to investigate cellular mechanisms and pathways involved in disease progression. Advanced research techniques and protocols enable detailed examination of SPRED protein expression and localization patterns. Ongoing studies of SPRED proteins continue to reveal new aspects of cellular regulation and potential therapeutic applications. Santa Cruz Biotechnology monoclonal antibodies for SPRED proteins support researchers in advancing scientific knowledge and developing innovative therapeutic strategies.

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SPRED Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SPRED1 Antibody (E-5)

sc-393198mouse IgG1 κ135-246 (h)WB, IP, IF, IHC(P), ELISAh
2
(4)

SPRED1 Antibody (M23-P2G3)

sc-101392mouse IgG1 κ420-428 (h)WB, IP, IF, ELISAm, r, h
2
(2)

SPRED1 Antibody (462CT2.5.1)

sc-517362mouse IgG1(h)WBm, r, h

new

(0)

SPRED2 Antibody (6G8)

sc-517018mouse IgG2a κ120-219 (h)WB, IP, ELISAh
1
(1)

SPRED siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPRED1 siRNA (h)

sc-90024hGene SilencingN/A
2
(0)

SPRED1 shRNA Plasmid (h)

sc-90024-SHhGene SilencingPuromycin
2
(0)

SPRED1 shRNA (h) Lentiviral Particles

sc-90024-VhGene SilencingPuromycin
2
(0)

SPRED1 siRNA (m)

sc-153783mGene SilencingN/A0
(0)

SPRED1 shRNA Plasmid (m)

sc-153783-SHmGene SilencingPuromycin0
(0)

SPRED1 shRNA (m) Lentiviral Particles

sc-153783-VmGene SilencingPuromycin0
(0)

SPRED2 siRNA (h)

sc-94969hGene SilencingN/A0
(0)

SPRED2 shRNA Plasmid (h)

sc-94969-SHhGene SilencingPuromycin0
(0)

SPRED2 shRNA (h) Lentiviral Particles

sc-94969-VhGene SilencingPuromycin0
(0)

SPRED2 siRNA (m)

sc-153784mGene SilencingN/A0
(0)

SPRED2 shRNA Plasmid (m)

sc-153784-SHmGene SilencingPuromycin0
(0)

SPRED2 shRNA (m) Lentiviral Particles

sc-153784-VmGene SilencingPuromycin0
(0)

SPRED3 siRNA (h)

sc-97920hGene SilencingN/A0
(0)

SPRED3 shRNA Plasmid (h)

sc-97920-SHhGene SilencingPuromycin0
(0)

SPRED3 shRNA (h) Lentiviral Particles

sc-97920-VhGene SilencingPuromycin0
(0)

SPRED3 siRNA (m)

sc-153785mGene SilencingN/A0
(0)

SPRED3 shRNA Plasmid (m)

sc-153785-SHmGene SilencingPuromycin0
(0)

SPRED3 shRNA (m) Lentiviral Particles

sc-153785-VmGene SilencingPuromycin0
(0)

SPRED CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SPRED1 CRISPR/Cas9 KO Plasmid (h)

sc-402981Gene Knockouth0
(0)

SPRED2 CRISPR/Cas9 KO Plasmid (h)

sc-404738Gene Knockouth0
(0)

SPRED2 CRISPR/Cas9 KO Plasmid (m)

sc-431133Gene Knockoutm0
(0)

SPRED2 HDR Plasmid (m)

sc-431133-HDRHomology Directed Repairm0
(0)

SPRED CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SPRED2 Double Nickase Plasmid (h)

sc-404738-NICGene Knockouth0
(0)

SPRED2 Double Nickase Plasmid (h2)

sc-404738-NIC-2Gene Knockouth0
(0)

SPRED2 Double Nickase Plasmid (m)

sc-431133-NICGene Knockoutm0
(0)

SPRED2 Double Nickase Plasmid (m2)

sc-431133-NIC-2Gene Knockoutm0
(0)

SPRED CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SPRED1 CRISPR Activation Plasmid (h)

sc-402981-ACTGene Activationh0
(0)

SPRED2 CRISPR Activation Plasmid (m)

sc-431133-ACTGene Activationm0
(0)

SPRED2 CRISPR Activation Plasmid (m2)

sc-431133-ACT-2Gene Activationm0
(0)