SPATA2 Inhibitors
SPATA2 inhibitors belong to a distinct chemical class designed to specifically target the SPATA2 protein. SPATA2, an acronym for Spermatogenesis Associated 2, plays a crucial role in cellular processes, particularly in innate immune responses and cell cycle regulation. These inhibitors are meticulously crafted molecules designed to interact with the SPATA2 protein, modulating its function or hindering its activity. Through precise molecular interactions, these inhibitors interfere with the normal function of SPATA2 within cellular pathways.
SPATA2 inhibitors involves intricate design processes and rigorous testing to ensure their specificity and effectiveness. Researchers employ various chemical synthesis and screening techniques to identify or design molecules capable of binding to the SPATA2 protein with high affinity and selectivity. Understanding the structural intricacies of SPATA2 and its interaction with these inhibitors is fundamental to their development. Through computational modeling and experimental validation, scientists aim to elucidate the binding mechanisms and optimize the chemical structures of these inhibitors for enhanced potency and reduced off-target effects. Overall, SPATA2 inhibitors represent a promising class of compounds with the potential to elucidate the biological functions of SPATA2 and serve as valuable tools for further research in cellular signaling pathways and immune responses.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Inhibits NF-κB activation by blocking phosphorylation and subsequent degradation of IκBα, thus affecting the pathway SPATA2 is involved in. | ||||||
NFκB Activation Inhibitor III | 380623-76-7 | sc-204818 | 5 mg | $115.00 | 3 | |
A selective NF-κB blocker that prevents the translocation of the p65 subunit of NF-κB to the nucleus, thereby potentially altering SPATA2 mediated signaling. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
Targets NF-κB signaling by inhibiting IκB kinase, which may indirectly affect SPATA2's role in this pathway. | ||||||
QNZ | 545380-34-5 | sc-200675 | 1 mg | $115.00 | 12 | |
Inhibits TNFα-induced NF-κB activation, which may influence the signaling processes associated with SPATA2. | ||||||
NFκB Activation Inhibitor II, JSH-23 | 749886-87-1 | sc-222061 sc-222061C sc-222061A sc-222061B | 5 mg 10 mg 50 mg 100 mg | $210.00 $252.00 $1740.00 $1964.00 | 34 | |
Blocks NF-κB nuclear translocation, which could modulate the signaling pathway SPATA2 is a part of. | ||||||
IMD 0354 | 978-62-1 | sc-203084 | 5 mg | $199.00 | 3 | |
Inhibits IKKβ, a kinase involved in NF-κB activation, potentially impacting SPATA2's associated signaling pathways. | ||||||
IKK-2 Inhibitor IV | 507475-17-4 | sc-203083 | 500 µg | $130.00 | 12 | |
An IKK-2 inhibitor that prevents NF-κB activation, and thus may indirectly affect SPATA2's role. | ||||||
BMS-345541 | 445430-58-0 | sc-221741 | 1 mg | $306.00 | 1 | |
Selectively inhibits IKKα and IKKβ, reducing NF-κB activation which SPATA2 may influence. | ||||||
IKK Inhibitor X | 431898-65-6 | sc-221742 | 5 mg | $345.00 | 3 | |
Targets IκB kinase, thereby potentially affecting NF-κB signaling and indirectly influencing SPATA2's activity. | ||||||
RO 106-9920 | 62645-28-7 | sc-203240 sc-203240A | 1 mg 5 mg | $138.00 $587.00 | 7 | |
A selective inhibitor of the NF-κB inducing kinase (NIK), which may alter the non-canonical NF-κB pathway where SPATA2 is implicated. | ||||||