SPATA13 Activators
Compounds such as Rhosin, NSC23766, ML141, and TGF-β1 target key elements in signaling pathways and cellular processes that are crucial for the regulation of the cytoskeleton and cell migration, areas where SPATA13 is likely involved. By modulating the activity of Rho GTPases, ROCK, Rac1, Cdc42, and TGF-β signaling, these compounds might indirectly enhance the functional role of SPATA13 in cellular reorganization and movement.
Furthermore, compounds that directly affect the actin cytoskeleton, such as Cytochalasin D, Latrunculin A, Jasplakinolide, Wiskostatin, CK-666, and Blebbistatin, provide insights into the potential modulation of SPATA13's activity in actin dynamics. By disrupting or stabilizing actin filaments, inhibiting N-WASP or the Arp2/3 complex, and affecting myosin II activity, these compounds can influence SPATA13's involvement in cytoskeletal reorganization and cell motility. Additionally, Forskolin, by enhancing cAMP levels, might also affect SPATA13-mediated signaling pathways, especially those related to cell motility and adhesion.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rhosin | 1173671-63-0 | sc-507401 | 25 mg | $555.00 | ||
Inhibits Rho GTPase activation. By targeting Rho GTPase signaling, it could indirectly influence SPATA13's role in cytoskeletal reorganization and cell migration. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin filaments. Could influence SPATA13's function in actin dynamics and cellular processes like migration. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Disrupts actin filaments. Potentially affects SPATA13's involvement in actin dynamics and cellular migration. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments. Potentially impacts SPATA13's role in actin dynamics and cell morphology regulation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Enhances cAMP levels. Might influence SPATA13-mediated signaling pathways, especially those related to cell motility. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Inhibits N-WASP. Affects actin polymerization and potentially SPATA13's role in cytoskeletal reorganization. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
Inhibits the Arp2/3 complex. Could influence SPATA13's involvement in actin filament branching and cell movement. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II. Affects cell motility processes where SPATA13 might play a role, especially in myosin-driven cell movement. | ||||||
Thymosin β4 | 77591-33-4 | sc-396076 sc-396076A | 1 mg 100 mg | $134.00 $7140.00 | ||
Influences TGF-β receptor signaling. Could impact SPATA13's function in cell migration and extracellular matrix interactions. | ||||||