SODD Activators, short for Suppressor of Death Domains Activators, represent a class of chemical compounds that play a significant role in cellular processes, particularly in regulating cell survival and apoptosis. These activators are designed to interact with a protein known as SODD, or Suppressor of Death Domains, which is an important mediator in the apoptosis signaling pathway. Apoptosis, often referred to as programmed cell death, is a crucial mechanism for maintaining tissue homeostasis and eliminating damaged or unwanted cells in multicellular organisms.
AtSODD Activators are characterized by their ability to bind to the SODD protein, thereby modulating its function. SODD itself is a protein adapter that can interact with other proteins involved in apoptosis, such as members of the tumor necrosis factor receptor (TNFR) superfamily. By binding to SODD, these activators can influence the downstream signaling pathways triggered by TNFR family members. This modulation can result in either the promotion or inhibition of apoptotic cell death, depending on the specific context and cellular conditions.SODD Activators have garnered attention in the field of cell biology and signal transduction due to their potential to fine-tune apoptosis-related processes. Their role in the intricate dance of cell survival and death highlights the complexity of cellular signaling pathways and underscores the importance of chemical tools like SODD Activators in unraveling the mysteries of cellular biology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMP-activated protein kinase (AMPK), which can influence various cellular pathways including those involving TNFR1. AMPK activation may enhance the activity of SODD by stabilizing TNFR1 in an inactive state. |