SMARCD3 Inhibitors
SMARCD3 inhibitors belong to a class of compounds designed to modulate the activity of the SMARCD3 protein, also known as BAF60C, which is a crucial subunit of the SWI/SNF chromatin remodeling complex. These inhibitors are developed with the aim of disrupting or altering the function of SMARCD3 within the chromatin remodeling complex. SMARCD3 plays a pivotal role in regulating gene expression by modifying the structure and accessibility of chromatin, thereby influencing various cellular processes. Inhibitors targeting SMARCD3 may interact with specific domains or regions of the protein, affecting its interactions with other components of the SWI/SNF complex or its ability to bind to chromatin. This modulation of SMARCD3's function can potentially lead to changes in gene expression profiles and cellular responses.
The study of SMARCD3 inhibitors provides valuable insights into the intricate mechanisms of chromatin remodeling and its impact on gene regulation, cellular development, and homeostasis. These inhibitors serve as important tools for researchers to investigate the roles of SMARCD3 and the SWI/SNF complex in diverse biological processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PFI 3 | 1819363-80-8 | sc-507340 | 10 mg | $300.00 | ||
A small molecule inhibitor reported to selectively target the bromodomain of SMARCD3, potentially affecting its interactions within the SWI/SNF complex. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
Although primarily known as a BET bromodomain inhibitor, JQ1 has also shown activity against SMARCD3's bromodomain, potentially impacting its role in chromatin remodeling. | ||||||
RVX 208 | 1044870-39-4 | sc-472700 | 10 mg | $340.00 | ||
While primarily targeting BET bromodomains, RVX-208 has demonstrated the ability to inhibit SMARCD3's bromodomain as well, potentially influencing gene expression regulation. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
While mainly recognized as a BET inhibitor, I-BET151 also displays inhibitory effects on SMARCD3's bromodomain, influencing its function in chromatin remodeling. | ||||||