SKI-1 Inhibitors
The chemical class of SKI-1 Inhibitors comprises various compounds that can potentially suppress or modulate the activity of SKI-1. This class includes specific inhibitors like PF-429242 and AEBSF, which target the proteolytic activity of SKI-1. Synthetic peptide inhibitors like Decanoyl-RVKR-CMK are designed to inhibit SKI-1's protease function directly.
Statins, such as Atorvastatin, Rosuvastatin, Fluvastatin, Pravastatin, and Simvastatin, are included due to their potential indirect effects on SKI-1 by modulating lipid metabolism pathways that SKI-1 regulates. Compounds that inhibit fatty acid synthesis, like Cerulenin and C75, could also indirectly impact SKI-1 activity. Natural compounds such as Betulinic Acid and Tannic Acid, known to influence cellular metabolism and pathways, are considered potential indirect inhibitors of SKI-1.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PF-429242 | 947303-87-9 | sc-507498 | 5 mg | $176.00 | ||
A specific inhibitor of SKI-1, known to block the enzyme's proteolytic activity, thereby inhibiting its function in the SREBP pathway. | ||||||
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $65.00 $122.00 $428.00 $851.00 $1873.00 $4994.00 | 33 | |
A serine protease inhibitor that could potentially inhibit SKI-1 activity. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $257.00 $505.00 | 9 | |
While primarily a statin, at high concentrations, it might indirectly inhibit SKI-1 activity by altering lipid metabolism pathways. | ||||||
Rosuvastatin | 287714-41-4 | sc-481834 | 10 mg | $145.00 | 8 | |
A statin that could potentially affect SKI-1 activity indirectly through its impact on cholesterol biosynthesis. | ||||||
Fluvastatin | 93957-54-1 | sc-279169 | 50 mg | $250.00 | ||
Another statin that might have an indirect inhibitory effect on SKI-1 by modulating lipid metabolism pathways. | ||||||
Pravastatin, Sodium Salt | 81131-70-6 | sc-203218 sc-203218A sc-203218B | 25 mg 100 mg 1 g | $69.00 $162.00 $787.00 | 2 | |
A statin that can influence cholesterol synthesis pathways and could indirectly inhibit SKI-1. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Similar to other statins, Simvastatin can affect cholesterol metabolism and might indirectly influence SKI-1 activity. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $161.00 $312.00 $1210.00 | 9 | |
An inhibitor of fatty acid synthase that might indirectly affect SKI-1 activity by altering lipid metabolism. | ||||||
C75 (racemic) | 191282-48-1 | sc-202511 sc-202511A sc-202511B | 1 mg 5 mg 10 mg | $72.00 $206.00 $290.00 | 9 | |
A compound known to inhibit fatty acid synthase, potentially affecting lipid metabolism and indirectly influencing SKI-1 activity. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
A naturally occurring pentacyclic triterpenoid that can modulate lipid metabolism, potentially affecting SKI-1 activity indirectly. | ||||||