Date published: 2026-4-1

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Sigma Antibodies

Santa Cruz Biotechnology provides a broad selection of Sigma monoclonal antibodies for targeting proteins involved in critical biological processes. Sigma monoclonal antibodies excel in various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Sigma monoclonal antibodies target proteins essential for cellular signaling, immune response, and metabolic regulation, advancing the understanding of disease mechanisms and therapeutic strategies. The precise detection and quantification capabilities enhance research in cancer biology, immunology, and neurobiology. Researchers can explore protein function and interaction with exceptional accuracy and reliability. Advanced visualization options include conjugates with horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), enabling diverse experimental approaches. each Sigma monoclonal antibody ensure consistent, reproducible results across multiple applications. Santa Cruz Biotechnology's Sigma monoclonal antibodies empower researchers worldwide to advance scientific knowledge and contribute to breakthrough discoveries in life science research.

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Sigma Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Sigma Receptor Antibody (B-5)

sc-137075mouse IgG1 κ136-169 (h)WB, IP, IF, IHC(P), ELISAm, r, h
77
(18)

Sigma Receptor Antibody (F-5)

sc-166392mouse IgG2b κFL (h)WB, IP, IF, ELISAm, r, h
8
(6)

Non-Mammalian Sigma Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Sigma 54 Antibody (33.7)

sc-73492mouse IgG1 κ(Aquifex aeolicus VF5)WBAquifex aeolicus VF5

new

(1)

Sigma 54 Antibody (Asigma54-33.7)

sc-53957mouse IgG1 κ(Aquifex aeolicus VF5)WBAquifex aeolicus VF5

new

(1)

Sigma CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sigma Receptor CRISPR/Cas9 KO Plasmid (h2)

sc-400615-KO-2hGene KnockoutGFP0
(0)

Sigma Receptor HDR Plasmid (h2)

sc-400615-HDR-2hHomology Directed RepairPuromycin0
(0)

Sigma Receptor Double Nickase Plasmid (h)

sc-400615-NIChGene KnockoutPuromycin0
(0)

Sigma Receptor Double Nickase Plasmid (h2)

sc-400615-NIC-2hGene KnockoutPuromycin0
(0)

Sigma Receptor CRISPR/Cas9 KO Plasmid (m)

sc-422068mGene KnockoutGFP
1
(0)

Sigma Receptor HDR Plasmid (m)

sc-422068-HDRmHomology Directed RepairPuromycin
1
(0)

Sigma Receptor Double Nickase Plasmid (m)

sc-422068-NICmGene KnockoutPuromycin
1
(0)

Sigma CRISPR Activation Products

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Sigma Receptor CRISPR Activation Plasmid (h)

sc-400615-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sigma Receptor CRISPR Activation Plasmid (h2)

sc-400615-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Sigma Receptor Lentiviral Activation Particles (h)

sc-400615-LAChGene ActivationPuro, Blast, Hygro0
(0)

Sigma Receptor Lentiviral Activation Particles (h2)

sc-400615-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Sigma Receptor CRISPR Activation Plasmid (m)

sc-422068-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

Sigma Receptor CRISPR Activation Plasmid (m2)

sc-422068-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

Sigma siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sigma Receptor siRNA (h)

sc-42250hGene SilencingN/A
8
(0)

Sigma Receptor shRNA Plasmid (h)

sc-42250-SHhGene SilencingPuromycin
8
(0)

Sigma Receptor shRNA (h) Lentiviral Particles

sc-42250-VhGene SilencingPuromycin
8
(0)

Sigma Receptor siRNA (m)

sc-42251mGene SilencingN/A
1
(0)

Sigma Receptor shRNA Plasmid (m)

sc-42251-SHmGene SilencingPuromycin
1
(0)

Sigma Receptor shRNA (m) Lentiviral Particles

sc-42251-VmGene SilencingPuromycin
1
(0)