Sigma 54 Antibody (Asigma54-33.7): sc-53957

Sigma 54 Antibody (Asigma54-33.7) is a mouse monoclonal IgG1 antibody that detects Sigma 54 of Aquifex aeolicus VF5 by western blotting (WB). Sigma 54 is a crucial subunit of bacterial RNA polymerase (RNAP) that plays a significant role in transcription activation when combined with other sigma factors. Sigma 54 binds to bacterial DNA at its C-terminus, functioning as a transcription regulator for sigma 54-dependent genes. Anti-Sigma 54 antibody (Asigma54-33.7) enables researchers to study how Sigma 54 modulates gene expression in response to environmental changes, which is vital for bacterial adaptation and survival. In organisms like Pseudomonas alcaligenes, Sigma 54 is instrumental in regulating a wide array of genes, thereby influencing various metabolic pathways and stress responses. Cellular concentration of Sigma 54 can vary throughout the organism′s lifecycle or in reaction to environmental pressures, highlighting its dynamic role in gene regulation. Sigma 54 monoclonal antibody (Asigma54-33.7) serves as an essential tool for researchers studying bacterial transcription mechanisms and the regulatory networks that govern gene expression in response to environmental stimuli.

The preferred Sigma 54 antibody is Sigma 54 Antibody (33.7): sc-73492.