SEMA4B Activators

SEMA4B, also known as Semaphorin-4B, is a protein that is encoded by the SEMA4B gene in humans. It belongs to the semaphorin family, a large family of proteins known for their role as guidance cues in the nervous system, guiding the growth of axons during the development of the nervous system.Semaphorins are characterized by a sema domain, a protein interaction module found in all family members. SEMA4B, like other class 4 semaphorins, is a transmembrane protein, meaning it is embedded in the cell membrane and can transmit signals across it.While initially studied for their roles in the nervous system, semaphorins are now known to be involved in various biological processes. They have been implicated in organogenesis, angiogenesis, immune responses, and cancer.

SEMA4B, in particular, is expressed in various tissues, with high levels observed in the brain, heart, and kidney. The exact functions of SEMA4B are not fully understood, but it's known to play roles in neuronal development and immune cell regulation. In summary, SEMA4B is a multifunctional protein involved in various biological processes, with implications for understanding the development and progression of several diseases, particularly those related to the nervous system and cancer.