S-100A14 Activators
S100 calcium-binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene. S100A14 belongs to the S100 family of proteins, which are known for their role in a wide range of intracellular and extracellular functions.S100 proteins are characterized by their ability to bind calcium ions, which can induce a conformational change and affect the protein's interaction with its targets. These proteins are involved in the regulation of a variety of cellular processes, such as cell cycle progression, differentiation, and the inflammatory response.
S100A14 is expressed in a wide range of tissues and is known to interact with a number of other proteins, influencing various cellular processes. It has been implicated in the regulation of cell growth and survival, and is thought to play a role in cell proliferation, apoptosis, and the cellular response to stress.Interestingly, S100A14 is also associated with several types of cancer. Its expression levels can vary significantly in different types of tumors and at different stages of cancer progression. In some cancers, such as breast and ovarian cancer, S100A14 expression has been associated with tumor progression and poor prognosis. However, in other types of cancer, such as colorectal cancer, S100A14 appears to act as a tumor suppressor.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin disrupts calcium storage in the endoplasmic reticulum, possibly impacting calcium-dependent proteins including S-100A14. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
Bisindolylmaleimide I is a PKC inhibitor, and by modulating PKC activity, it might indirectly influence S-100A14 function. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $458.00 | 61 | |
BAPTA-AM is a cell-permeable calcium chelator, which can modulate intracellular calcium levels, potentially affecting S-100A14. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels, which can affect a range of cellular processes, potentially including those associated with S-100A14. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent PKC inhibitor and affects various kinases, which could indirectly impact S-100A14 activity. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl-cAMP, a cAMP analog, can mimic the action of cAMP and modulate cellular processes potentially linked with S-100A14. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine is a calcium channel blocker that might influence calcium signaling pathways related to S-100A14 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride inhibits GSK-3, which is involved in numerous signaling pathways, potentially impacting S-100A14 activity. | ||||||