RTP4 Activators
RTP4, also known as Receptor Transporter Protein 4, is a member of the RTP family that is known for its role in the trafficking and functional expression of odorant receptors on the cell surface. RTP4, along with other members of the RTP family, is primarily expressed in the olfactory epithelium and has been implicated in the chemosensory system, particularly in the olfactory signaling pathways.
The protein is involved in the transport and proper localization of G protein-coupled receptors (GPCRs), which are critical for the detection of odorant molecules. RTP4 assists in the translocation of these receptors from the endoplasmic reticulum to the plasma membrane, enabling the detection of odorants by olfactory sensory neurons. This function is essential for the sense of smell, which relies on the binding of odorant molecules to their corresponding GPCRs on the surface of olfactory neuronsBeyond its role in olfaction, RTP4 may have broader implications in GPCR biology, given that GPCRs represent a large family of receptors involved in various physiological responses. RTP4 could potentially influence the pharmacological properties of GPCRs and affect drug efficacy and specificity by affecting receptor trafficking and expression levels.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels, which may indirectly influence RTP4 by modulating cAMP-dependent pathways. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
A cAMP analog that bypasses adenylyl cyclase activation, potentially affecting RTP4 activity through cAMP-mediated signaling pathways. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
A non-specific inhibitor of phosphodiesterases, IBMX raises intracellular cAMP levels, which could indirectly modulate RTP4. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
PGE2 interacts with its receptors to modulate adenylate cyclase activity, potentially influencing RTP4 through cAMP-dependent mechanisms. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram is a selective phosphodiesterase 4 inhibitor, increasing cAMP levels, thereby potentially affecting RTP4. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cAMP analog that can modulate cAMP-dependent signaling, possibly influencing RTP4 activity. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Through its receptors, adenosine can modulate adenylate cyclase activity, potentially influencing RTP4 via cAMP pathways. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Acts on adrenergic receptors, influencing adenylate cyclase and cAMP levels, which may indirectly affect RTP4. | ||||||
PGE1 (Prostaglandin E1) | 745-65-3 | sc-201223 sc-201223A | 1 mg 10 mg | $30.00 $142.00 | 16 | |
Activates adenylate cyclase via its receptor, potentially influencing RTP4 through cAMP-mediated pathways. | ||||||