Date published: 2026-4-4

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Rock Inhibitors

Santa Cruz Biotechnology now offers a broad range of Rock inhibitors for use in various applications. Rock inhibitors are chemical compounds that target Rho-associated protein kinases (ROCKs), which are critical enzymes involved in regulating the cytoskeleton and cellular processes such as contraction, motility, proliferation, and apoptosis. These inhibitors are widely utilized in scientific research to dissect the roles of ROCKs in cell biology and to explore their influence on cellular signaling pathways. They are especially valuable in studies focusing on cell migration, adhesion, and morphological changes, providing insights into fundamental biological processes and disease mechanisms. Researchers employ Rock inhibitors to modulate cellular functions in various model systems, facilitating the exploration of mechanistic pathways and the identification of potential biomarkers or targets for further investigation. The use of Rock inhibitors has been instrumental in advancing our understanding of cellular dynamics and has contributed significantly to the development of new experimental approaches and technologies in the field of cell and molecular biology. View detailed information on our available Rock inhibitors by clicking on the product name.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632 dihydrochloride

129830-38-2sc-216067
sc-216067A
1 mg
5 mg
$170.00
$439.00
5
(2)

Y-27632 dihydrochloride serves as a selective inhibitor of Rho-associated protein kinase (ROCK), showcasing intriguing molecular dynamics. Its structure facilitates specific interactions with target proteins, enabling the formation of stable complexes that alter enzymatic activity. The compound's unique hydrophilic and lipophilic balance enhances solubility, promoting effective diffusion across membranes. This characteristic, combined with its ability to modulate protein conformations, underscores its role in influencing cellular pathways.

Y-27632-d4

sc-220394
sc-220394A
1 mg
10 mg
$286.00
$2448.00
(0)

Y-27632-d4 exhibits distinctive properties as a ROCK inhibitor, characterized by its isotopic labeling that enhances tracking in biochemical assays. This compound engages in specific hydrogen bonding and hydrophobic interactions, which stabilize its binding to target proteins. Its unique isotopic composition allows for precise kinetic studies, revealing insights into reaction mechanisms. Additionally, the compound's structural rigidity contributes to its selectivity, influencing downstream signaling pathways effectively.