RHOBTB1 inhibitors belong to a specialized class of chemical compounds that primarily target the protein RHOBTB1. RHOBTB1, short for Rho-related BTB domain-containing protein 1, is a key regulatory protein involved in various cellular processes, particularly those associated with the dynamics of the cytoskeleton and cell division. The inhibition of RHOBTB1, typically achieved through small molecules or compounds, can have significant implications for cellular functions and may serve as a valuable tool for research purposes. These inhibitors are designed to interfere with the normal functioning of RHOBTB1, often by disrupting its binding to other cellular proteins or modifying its activity.
RHOBTB1 inhibitors can vary, but their common goal is to modulate the activity of RHOBTB1 within the cell. By inhibiting RHOBTB1, these compounds can influence processes like cell migration, cell adhesion, and cell division, which are essential for various physiological and pathological events. Researchers employ RHOBTB1 inhibitors in experimental settings to gain insights into the role of RHOBTB1 in cellular pathways, particularly in cancer research and studies related to cellular motility. The development of specific RHOBTB1 inhibitors has expanded our understanding of this protein's intricate role in cellular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor, Y-27632 can indirectly affect RHOBTB1 by inhibiting Rho-associated protein kinase, potentially altering the downstream effects of RHOBTB1-regulated pathways. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
A CDC42 inhibitor, ML141 may affect RHOBTB1 function indirectly through modulation of CDC42, a known regulator of the Rho GTPase family. | ||||||
Rhosin | 1173671-63-0 | sc-507401 | 25 mg | $555.00 | ||
Rhosin directly binds to RhoA and inhibits its activation. As RHOBTB1 is related to RhoA, this could indirectly alter RHOBTB1's activity or regulation. | ||||||
EHT 1864 | 754240-09-0 | sc-361175 sc-361175A | 10 mg 50 mg | $209.00 $872.00 | 12 | |
This compound is a Rac1 GTPase inhibitor, potentially modulating the activity of related RHOBTB1 pathways through its effects on Rac1. | ||||||
ITX 3 | 347323-96-0 | sc-295214 sc-295214A | 10 mg 50 mg | $145.00 $615.00 | ||
ITX3 is a non-competitive inhibitor of TrioN, which is a guanine nucleotide exchange factor for Rac1, thereby it can indirectly affect RHOBTB1 signaling. | ||||||
CASIN | 425399-05-9 | sc-397016 | 10 mg | $460.00 | 1 | |
CASIN inhibits Cdc42, potentially altering the signaling pathways that RHOBTB1 is involved in, given the interconnected nature of Rho GTPase family members. | ||||||
AZA1 | 1071098-42-4 | sc-507497 | 10 mg | $600.00 | ||
This compound inhibits Rac1 activation, potentially affecting pathways and processes regulated by RHOBTB1. | ||||||
ZCL278 | 587841-73-4 | sc-507369 | 10 mg | $115.00 | ||
A CDC42 inhibitor, ZCL278 could impact RHOBTB1 indirectly by altering CDC42-related signaling and cellular functions. | ||||||