Date published: 2026-3-31

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RBM41 Inhibitors

Inhibitors targeting the RBM41 protein function through a diverse range of biological pathways. Some compounds achieve their inhibitory action by blocking crucial phosphorylation events that are necessary for the protein's interaction with other cellular components. Others may disrupt key signaling pathways that regulate protein synthesis, which could result in a decrease in the production or activity of the protein. Certain antimetabolites have the potential to impact the protein by modifying its RNA substrates, consequently interfering with its ability to bind RNA effectively.

Additionally, a selection of compounds can interfere with the transcription and translation processes essential for the synthesis of the protein, thus leading to its reduced presence in the cell. Some of these compounds may impede pathways that are vital for the stability or functionality of the protein, thereby affecting its role in RNA processing. Others directly target the splicing machinery of the cell, which is integral to the protein's function in RNA splicing. Compounds that influence chromatin structure and transcription dynamics could also result in altered expression levels of the protein. Furthermore, inhibitors that affect the operation of molecular chaperones, which assist in the stabilization and proper folding of proteins, could lead to a decrease in the functional activity of the protein.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

This kinase inhibitor impedes phosphorylation events that RBM41 may be involved in, thereby potentially inhibiting RBM41's interaction with other proteins or RNA.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

This compound inhibits PI3K, which is a part of the PI3K/AKT/mTOR pathway; suppression of this pathway can decrease the translation of certain RNA binding proteins including RBM41.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

Disrupts RNA processing and could interfere with the RNA binding activity of RBM41 by altering RNA substrates.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Interacts with DNA and inhibits RNA polymerase, which could reduce the transcription of RBM41.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Inhibits RNA polymerase II, which could lead to a decrease in RBM41 mRNA synthesis and thus lower RBM41 protein levels.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis by interfering with the translocation step in protein synthesis, potentially reducing RBM41 levels.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Inhibits mTOR, which may lead to reduced synthesis of RNA binding proteins like RBM41 through the mTOR pathway's control of cap-dependent translation.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

A MEK inhibitor that can disrupt the downstream ERK pathway, potentially affecting the synthesis or function of RNA binding proteins such as RBM41.

Spliceostatin A

391611-36-2sc-507481
1 mg
$1800.00
(0)

This compound disrupts splicing by inhibiting the spliceosome, which could impact RBM41's role in RNA splicing and processing.

Pladienolide B

445493-23-2sc-391691
sc-391691B
sc-391691A
sc-391691C
sc-391691D
sc-391691E
0.5 mg
10 mg
20 mg
50 mg
100 mg
5 mg
$299.00
$5699.00
$11099.00
$25500.00
$66300.00
$2875.00
63
(2)

Targets the spliceosomal SF3b complex and may alter splicing efficiency or specificity, potentially affecting RBM41's RNA splicing activity.