Rab L2A Activators
Rab L2A, also known as Rab-like protein 2A (gene name: RABL2A), is a member of the Rab family of small GTPases, which are key regulators of intracellular membrane trafficking in eukaryotic cells. Rab proteins are known to control various steps of membrane transport, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion. They achieve this by cycling between an active GTP-bound state and an inactive GDP-bound state, with the help of GEFs (guanine nucleotide exchange factors) and GAPs (GTPase-activating proteins).
Rab L2A, in particular, is thought to be involved in the transport of vesicles within cells and may be implicated in specific trafficking pathways. While the precise function of Rab L2A is not as well-characterized as some of the other members of the Rab family, it is likely to play a role in ensuring the proper delivery of cargo within the cell, which is crucial for maintaining cellular function and homeostasis.The Rab GTPases, as a family, are involved in many critical cellular processes, including endocytosis, exocytosis, and the recycling of membrane receptors, which are vital for cell signaling and nutrient uptake. Dysregulation of Rab protein function has been associated with various diseases, including immune disorders, cancer, and neurodegenerative diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises cAMP levels, which might indirectly influence Rab L2A by modulating cellular signaling pathways. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A disrupts vesicle formation and can indirectly affect Rab L2A function in vesicle trafficking. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin, an ionophore that disrupts endosomal transport, may indirectly influence Rab L2A's role in vesicle trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules and can impact vesicle transport pathways, potentially affecting Rab L2A activity. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules, potentially influencing Rab L2A's role in microtubule-dependent vesicle transport. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, a PI3K inhibitor, may indirectly affect Rab L2A by altering intracellular signaling and vesicle trafficking. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynasore inhibits dynamin, impacting endocytosis and vesicle trafficking, potentially influencing Rab L2A function. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
ML141 is a Cdc42 inhibitor, potentially affecting actin dynamics and indirectly influencing Rab L2A in vesicle trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D disrupts actin filaments, potentially affecting vesicle transport and Rab L2A's role in this process. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ is involved in numerous cellular processes, and its availability may indirectly influence Rab L2A function. | ||||||