Date published: 2026-5-14

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Psoriasin Inhibitors

Psoriasin inhibitors belong to a distinct chemical class that targets the protein psoriasin (also known as S100A7). Psoriasin is a member of the S100 calcium-binding protein family and is involved in various inflammatory processes, particularly in skin conditions like psoriasis. The inhibitors designed to interact with psoriasin are carefully crafted to specifically hinder or modulate its activity without interfering with other cellular functions.

These inhibitors can vary in their chemical structures, with each possessing unique molecular features that allow them to bind to specific sites on the psoriasin protein. Through this interaction, psoriasin inhibitors aim to regulate the signaling pathways or molecular cascades influenced by psoriasin, ultimately leading to potential effects on the inflammatory response associated with psoriasis. Ongoing research seeks to further elucidate the mechanisms of action and explore the full scope of psoriasin inhibitors as potential tools in the management of conditions influenced by psoriasin expression.

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Baricitinib

1187594-09-7sc-364730
sc-364730A
5 mg
25 mg
$200.00
$664.00
(1)

An inhibitor that can modulate the activity of psoriasin, which was under investigation by Eli Lilly and Company.

Niclosamide

50-65-7sc-250564
sc-250564A
sc-250564B
sc-250564C
sc-250564D
sc-250564E
100 mg
1 g
10 g
100 g
1 kg
5 kg
$38.00
$79.00
$188.00
$520.00
$1248.00
$5930.00
8
(1)

Originally an antiparasitic drug, niclosamide was identified as an inhibitor of psoriasin, showing anti-inflammatory properties.

Indirubin

479-41-4sc-201531
sc-201531A
5 mg
25 mg
$114.00
$525.00
4
(1)

A naturally occurring compound with anti-inflammatory properties that have shown to inhibit psoriasin expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

An active compound found in turmeric, curcumin has demonstrated inhibitory effects on psoriasin in research studies.