PRR12 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a beta-adrenergic agonist that leads to the activation of adenylyl cyclase via G protein-coupled receptor signaling, consequently raising cAMP levels and activating PKA. PKA activation can lead to phosphorylation and activation of proteins, potentially including PRR12. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a nonspecific inhibitor of phosphodiesterases, which increases cAMP by preventing its degradation. Elevated cAMP activates PKA, leading to phosphorylation and potential activation of downstream proteins such as PRR12. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 (PGE2) activates G protein-coupled receptors that can increase cAMP levels in cells via adenylyl cyclase activation. This rise in cAMP may activate PKA, which in turn could phosphorylate and activate PRR12. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine acts on adrenergic receptors, leading to adenylyl cyclase activation and increased cAMP levels. Through cAMP's activation of PKA, subsequent phosphorylation and activation of proteins like PRR12 could occur. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a protein synthesis inhibitor that also activates stress-activated protein kinases, like JNK, which might lead to the activation of transcription factors and other proteins, potentially including PRR12, as part of the cellular stress response. | ||||||
PACAP(6-38) | 137061-48-4 | sc-391136 sc-391136A | 500 µg 1 mg | $540.00 $932.00 | ||
Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) binds to its GPCR, leading to adenylyl cyclase activation and an increase in cAMP, which activates PKA. PKA could then phosphorylate and activate PRR12. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine can activate H2 receptors, which positively couple to adenylyl cyclase, increasing cAMP and activating PKA. Activated PKA may phosphorylate and activate PRR12 as part of a signaling pathway. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram inhibits PDE4, leading to increased cAMP levels and subsequent PKA activation. PKA can phosphorylate various proteins and might phosphorylate and activate PRR12. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine can activate dopamine D1 receptors, which are coupled to Gs proteins that stimulate adenylyl cyclase, raising cAMP levels and activating PKA. PKA could then phosphorylate and activate PRR12. | ||||||