Date published: 2026-4-24

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Prolyl Hydroxylase Antibodies

Santa Cruz Biotechnology delivers a wide array of Prolyl Hydroxylase monoclonal antibodies for investigating prolyl hydroxylases in various biological processes. Prolyl Hydroxylase Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Prolyl hydroxylases are essential enzymes involved in the post-translational modification of proteins, particularly in the hydroxylation of proline residues in collagen and other proteins. The hydroxylation process is fundamental for collagen stability and function, impacting wound healing, tissue repair, and cellular responses to hypoxia. Prolyl hydroxylases have emerged as significant factors in various physiological and pathological conditions, including fibrosis and cancer. Researchers can utilize specific monoclonal antibodies to examine the expression, localization, and interactions of prolyl hydroxylases across different experimental conditions. Understanding prolyl hydroxylase activity and regulation can provide valuable insights into disease mechanisms and potential therapeutic strategies. The extensive selection of monoclonal antibodies from Santa Cruz Biotechnology enables researchers worldwide to advance scientific understanding of prolyl hydroxylases and their impact on human health.

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Prolyl Hydroxylase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HIF PHD1 Antibody (2G3)

sc-293220mouse IgG2a κFL (h)WB, IP, IF, IHC(P), ELISAh
1
(1)

HIF PHD2 Antibody (H-8)

sc-271835mouse IgG1 κ240-288 (h)WB, IP, IF, ELISAm, r, h
20
(13)

HIF PHD3 Antibody (EG188e/d5)

sc-517601mouse IgG1 κ1-100 (h)WB, IP, IF, IHC(P)h

new

(2)

Prolyl Hydroxylase CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF PHD1 CRISPR/Cas9 KO Plasmid (h2)

sc-402824-KO-2hGene KnockoutGFP0
(0)

HIF PHD1 Double Nickase Plasmid (h)

sc-402824-NIChGene KnockoutPuromycin0
(0)

HIF PHD1 Double Nickase Plasmid (h2)

sc-402824-NIC-2hGene KnockoutPuromycin0
(0)

HIF PHD1 CRISPR/Cas9 KO Plasmid (m)

sc-431082mGene KnockoutGFP0
(0)

HIF PHD1 HDR Plasmid (m)

sc-431082-HDRmHomology Directed RepairPuromycin0
(0)

HIF PHD2 CRISPR/Cas9 KO Plasmid (h)

sc-403334hGene KnockoutGFP
1
(0)

HIF PHD2 HDR Plasmid (h)

sc-403334-HDRhHomology Directed RepairPuromycin
1
(0)

HIF PHD2 Double Nickase Plasmid (h)

sc-403334-NIChGene KnockoutPuromycin
1
(0)

HIF PHD2 Double Nickase Plasmid (h2)

sc-403334-NIC-2hGene KnockoutPuromycin
1
(0)

HIF PHD2 CRISPR/Cas9 KO Plasmid (m)

sc-431081mGene KnockoutGFP
1
(0)

HIF PHD2 HDR Plasmid (m)

sc-431081-HDRmHomology Directed RepairPuromycin
1
(0)

HIF PHD2 Double Nickase Plasmid (m)

sc-431081-NICmGene KnockoutPuromycin
1
(0)

HIF PHD3 CRISPR/Cas9 KO Plasmid (h)

sc-403671hGene KnockoutGFP0
(0)

HIF PHD3 Double Nickase Plasmid (m)

sc-431083-NICmGene KnockoutPuromycin0
(0)

Prolyl Hydroxylase CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF PHD2 CRISPR Activation Plasmid (h)

sc-403334-ACThGene ActivationPuro, Blast, Hygro
1
(0)

HIF PHD3 CRISPR Activation Plasmid (h)

sc-403671-ACThGene ActivationPuro, Blast, Hygro0
(0)

HIF PHD3 CRISPR Activation Plasmid (h2)

sc-403671-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HIF PHD3 Lentiviral Activation Particles (h)

sc-403671-LAChGene ActivationPuro, Blast, Hygro0
(0)

HIF PHD3 Lentiviral Activation Particles (h2)

sc-403671-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

HIF PHD3 CRISPR Activation Plasmid (m2)

sc-431083-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HIF PHD3 Lentiviral Activation Particles (m)

sc-431083-LACmGene ActivationPuro, Blast, Hygro0
(0)

HIF PHD3 Lentiviral Activation Particles (m2)

sc-431083-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PHD3 CRISPR Activation Plasmid (m)

sc-431083-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Prolyl Hydroxylase siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF PHD1 siRNA (h)

sc-45616hGene SilencingN/A
4
(0)

HIF PHD1 shRNA Plasmid (h)

sc-45616-SHhGene SilencingPuromycin
4
(0)

HIF PHD1 shRNA (h) Lentiviral Particles

sc-45616-VhGene SilencingPuromycin
4
(0)

HIF PHD1 siRNA (m)

sc-45617mGene SilencingN/A
1
(0)

HIF PHD1 shRNA Plasmid (m)

sc-45617-SHmGene SilencingPuromycin
1
(0)

HIF PHD1 shRNA (m) Lentiviral Particles

sc-45617-VmGene SilencingPuromycin
1
(0)

HIF PHD2 siRNA (h)

sc-45537hGene SilencingN/A
10
(0)

HIF PHD2 shRNA Plasmid (h)

sc-45537-SHhGene SilencingPuromycin
10
(0)

HIF PHD2 shRNA (h) Lentiviral Particles

sc-45537-VhGene SilencingPuromycin
10
(0)

HIF PHD2 siRNA (m)

sc-45538mGene SilencingN/A
1
(0)

HIF PHD2 shRNA Plasmid (m)

sc-45538-SHmGene SilencingPuromycin
1
(0)

HIF PHD2 shRNA (m) Lentiviral Particles

sc-45538-VmGene SilencingPuromycin
1
(0)

HIF PHD3 siRNA (h)

sc-45799hGene SilencingN/A
5
(0)

HIF PHD3 shRNA Plasmid (h)

sc-45799-SHhGene SilencingPuromycin
5
(0)

HIF PHD3 shRNA (h) Lentiviral Particles

sc-45799-VhGene SilencingPuromycin
5
(0)

HIF PHD3 siRNA (m)

sc-45800mGene SilencingN/A
2
(0)

HIF PHD3 shRNA Plasmid (m)

sc-45800-SHmGene SilencingPuromycin
2
(0)

HIF PHD3 shRNA (m) Lentiviral Particles

sc-45800-VmGene SilencingPuromycin
2
(0)