Date published: 2025-9-10

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PRAME like-4 Inhibitors

PRAME-like 4 inhibitors are a class of chemical compounds designed to specifically target and inhibit the activity of the PRAME-like 4 protein, a member of the PRAME (Preferentially Expressed Antigen in Melanoma) family of proteins. The PRAME family is known to be involved in various cellular processes, particularly those related to gene regulation. PRAME-like 4 is thought to play a role in transcriptional repression, likely through interactions with other regulatory proteins or transcription factors. By binding to these regulatory components, PRAME-like 4 may modulate gene expression patterns that are crucial for maintaining cellular function. Inhibitors of PRAME-like 4 function by blocking its ability to interact with these transcriptional complexes, thereby altering its role in gene regulation.

Using PRAME-like 4 inhibitors in research helps scientists investigate the specific molecular mechanisms underlying its role in transcriptional regulation. These inhibitors allow researchers to explore how the disruption of PRAME-like 4 activity impacts cellular gene expression profiles, shedding light on its contributions to broader regulatory networks. By inhibiting PRAME-like 4, scientists can examine changes in protein interactions, chromatin remodeling, and overall transcriptional control within the cell. Additionally, studying these inhibitors provides insights into how PRAME-like 4 fits into the complex network of proteins that regulate gene expression, offering a deeper understanding of its role in maintaining cellular homeostasis and responding to environmental signals. This research ultimately helps unravel the precise functions of PRAME-like 4 in cellular processes such as differentiation, proliferation, and signaling.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate might disrupt folate metabolism, resulting in altered nucleotide synthesis and potentially increasing the transcription of genes like PRAME like-4.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide inhibits protein synthesis, which could create feedback loops that inadvertently lead to the enhanced transcription of PRAME like-4.