Date published: 2026-4-16

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PP2 Activators

Santa Cruz Biotechnology now offers a broad range of PP2 Activators for use in various applications. PP2 activators are compounds that specifically enhance the activity of Protein Phosphatase 2 (PP2), a key enzyme in the regulation of cellular functions through dephosphorylation of serine and threonine residues in proteins. These activators are vital tools in scientific research, particularly in studies focused on signal transduction pathways, cell cycle regulation, and metabolic control. PP2 is a multifunctional enzyme involved in numerous physiological processes, including the modulation of signaling cascades that control cell growth, differentiation, and apoptosis. By selectively activating PP2, researchers can dissect the specific roles of this phosphatase in various cellular contexts, providing insights into fundamental biological mechanisms. Moreover, PP2 activators are essential in exploring the regulatory networks of kinases and phosphatases, which are critical for maintaining cellular homeostasis. Their use extends to structural biology, where they aid in explaining the conformational changes and substrate interactions of PP2, thus contributing to our understanding of enzyme regulation at a molecular level. View detailed information on our available PP2 Activators by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ceramide C6

124753-97-5sc-3527
sc-3527A
5 mg
25 mg
$90.00
$337.00
42
(1)

Ceramide C6, a sphingolipid derivative, exhibits unique interactions with cellular membranes, influencing lipid bilayer dynamics. As a PP2 inhibitor, it engages in specific hydrogen bonding and hydrophobic interactions that stabilize its conformation within the enzyme's active site. This binding alters the enzyme's structural integrity, affecting its catalytic activity and modulating various signaling pathways. The distinct fatty acid chain length of Ceramide C6 contributes to its selective affinity and functional versatility in cellular processes.

C2 Ceramide

3102-57-6sc-201375
sc-201375A
5 mg
25 mg
$124.00
$460.00
12
(1)

C2 Ceramide, a sphingolipid, plays a pivotal role in cellular signaling by modulating membrane fluidity and composition. Its unique hydrophobic tail facilitates integration into lipid bilayers, impacting membrane curvature and protein interactions. As a PP2 inhibitor, it engages in specific van der Waals forces and electrostatic interactions, which can alter enzyme conformation and activity. This ceramide's short chain length enhances its rapid diffusion and accessibility within cellular environments, influencing various biochemical pathways.