Potassium Channel Modulators
Items 61 to 70 of 103 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Levcromakalim | 94535-50-9 | sc-361230 sc-361230A | 10 mg 50 mg | $437.00 $1380.00 | 2 | |
Levcromakalim functions as a potassium channel modulator by selectively binding to ATP-sensitive potassium channels, leading to increased potassium ion permeability. Its structural configuration enables specific interactions with channel proteins, which can alter the conformational states of the channels. This compound demonstrates notable reaction kinetics, allowing for prompt adjustments in cellular ion homeostasis. Furthermore, its hydrophobic characteristics enhance its affinity for lipid bilayers, influencing channel activity and ion flow. | ||||||
Charybdotoxin | 95751-30-7 | sc-200979 | 100 µg | $401.00 | 9 | |
Charybdotoxin is a potent modulator of voltage-gated potassium channels, exhibiting high specificity for certain channel subtypes. Its unique binding mechanism involves interactions with the channel's pore region, effectively blocking ion flow and altering membrane potential. This toxin's distinct structural features facilitate strong electrostatic interactions with channel residues, leading to significant changes in channel gating dynamics. Additionally, its stability in physiological conditions allows for prolonged effects on cellular excitability. | ||||||
Linopirdine dihydrochloride | 113168-57-3 | sc-204058 sc-204058A | 10 mg 50 mg | $165.00 $700.00 | ||
Linopirdine dihydrochloride acts as a selective modulator of potassium channels, influencing their gating properties through specific interactions with channel subunits. Its unique structure enables it to stabilize open conformations, enhancing ion conductance. The compound exhibits rapid kinetics in channel activation, allowing for fine-tuning of neuronal excitability. Furthermore, its ability to selectively target certain potassium channel isoforms underscores its potential for nuanced modulation of cellular signaling pathways. | ||||||
E-4031 dihydrochloride | 113559-13-0 | sc-203034 | 5 mg | $292.00 | 1 | |
E-4031 dihydrochloride is a potent modulator of potassium channels, characterized by its ability to selectively inhibit specific channel types. This compound interacts with the channel's voltage-sensing domains, altering their conformational dynamics and prolonging the open state. Its unique binding affinity leads to distinct kinetic profiles, allowing for precise control over ion flow. Additionally, E-4031's selectivity for certain potassium channel subtypes highlights its role in fine-tuning cellular electrical activity. | ||||||
XE 991 dihydrochloride | 122955-42-4 | sc-203453 sc-203453A | 10 mg 50 mg | $176.00 $733.00 | ||
XE 991 dihydrochloride is a selective modulator of potassium channels, known for its unique interaction with the channel's pore region. This compound stabilizes specific conformations, influencing ion permeability and gating kinetics. Its distinct binding characteristics enable it to fine-tune channel activity, resulting in altered ion flux dynamics. The compound's ability to selectively target certain potassium channel isoforms underscores its potential for nuanced modulation of cellular excitability. | ||||||
Y-26763 | 127408-31-5 | sc-204406 sc-204406A | 10 mg 50 mg | $175.00 $709.00 | ||
Y-26763 is a sophisticated potassium channel modulator that exhibits a unique binding affinity for the channel's voltage-sensing domains. This interaction leads to a modulation of the channel's activation threshold, effectively altering the kinetics of ion conduction. Its selective engagement with specific channel subtypes allows for precise control over membrane potential dynamics, influencing cellular signaling pathways. The compound's distinct molecular architecture contributes to its ability to fine-tune channel responsiveness under varying physiological conditions. | ||||||
Repaglinide | 135062-02-1 | sc-219959 sc-219959A sc-219959B | 100 mg 250 mg 1 g | $219.00 $422.00 $1358.00 | 3 | |
Repaglinide functions as a potassium channel modulator by selectively interacting with the channel's pore region, influencing ion flow and channel gating mechanisms. Its unique structural features enable it to stabilize specific conformations of the channel, thereby affecting the kinetics of ion transport. This modulation can lead to altered electrical activity in cells, showcasing its potential to finely adjust cellular excitability and signaling in response to varying ionic environments. | ||||||
UK-78282 monohydrochloride | 136647-02-4 | sc-253820 | 5 mg | $175.00 | ||
UK-78282 monohydrochloride acts as a potassium channel modulator by engaging with specific binding sites on the channel, leading to conformational changes that influence ion permeability. Its distinct molecular architecture allows for selective interaction with various channel subtypes, impacting the kinetics of channel opening and closing. This modulation can result in nuanced alterations in membrane potential and cellular signaling pathways, highlighting its role in fine-tuning ionic homeostasis. | ||||||
Kaliotoxin | 145199-73-1 | sc-362754 | 10 µg | $98.00 | ||
Kaliotoxin functions as a potassium channel modulator by selectively binding to the channel's pore region, inducing structural rearrangements that affect ion flow. Its unique peptide composition enables high specificity for certain potassium channel isoforms, altering gating dynamics and ion selectivity. This interaction can significantly influence cellular excitability and signal transduction, showcasing its intricate role in regulating electrochemical gradients across membranes. | ||||||
Mitiglinide Calcium | 145375-43-5 | sc-204808 sc-204808A | 100 mg 250 mg | $168.00 $315.00 | ||
Mitiglinide Calcium acts as a potassium channel modulator by engaging with specific binding sites on the channel, leading to conformational changes that impact ion permeability. Its unique structural features facilitate selective interactions with various potassium channel subtypes, influencing their activation and inactivation kinetics. This modulation can alter cellular ionic homeostasis, thereby affecting membrane potential and overall cellular function, highlighting its complex role in ion channel regulation. | ||||||