Molecular structure of Mitiglinide Calcium, CAS Number: 145375-43-5
Mitiglinide Calcium (CAS 145375-43-5)
Alternate Names:
Kad-1229
Application:
Mitiglinide Calcium is a closer of K+-ATP channels
CAS Number:
145375-43-5
Purity:
98%
Molecular Weight:
668.88
Molecular Formula:
2(C19H24NO3)•Ca
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Mitiglinide Calcium functions as a potassium channel blocker. It acts by binding to the ATP-sensitive potassium channels on the pancreatic beta cells, leading to the closure of these channels. This closure results in the depolarization of the cell membrane, leading to the opening of voltage-gated calcium channels. The influx of calcium ions then triggers the release of insulin from the beta cells. Mitiglinide Calcium′s mechanism of action involves targeting the pancreatic beta cells and modulating their insulin release in response to glucose levels. By interacting with the potassium channels and calcium channels, Mitiglinide Calcium plays a role in regulating insulin secretion at the cellular level.
Mitiglinide Calcium (CAS 145375-43-5) References
- Gastroretentive Microsponge as a Promising Tool for Prolonging the Release of Mitiglinide Calcium in Type-2 Diabetes Mellitus: Optimization and Pharmacokinetics Study. | Mahmoud, DBED., et al. 2018. AAPS PharmSciTech. 19: 2519-2532. PMID: 29948984
- Gastroretentive Cosolvent-Based In Situ Gel as a Promising Approach for Simultaneous Extended Delivery and Enhanced Bioavailability of Mitiglinide Calcium. | Mahmoud, DB., et al. 2019. J Pharm Sci. 108: 897-906. PMID: 30267785
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mitiglinide Calcium, 100 mg | sc-204808 | 100 mg | $168.00 | |||
Mitiglinide Calcium, 250 mg | sc-204808A | 250 mg | $315.00 |