Date published: 2025-10-21

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PLEKHG Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PLEKHG monoclonal antibodies for research focused on understanding the PLEKHG protein family. PLEKHG monoclonal antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PLEKHG proteins function as guanine nucleotide exchange factors (GEFs) for Rho GTPases, playing essential roles in regulating cytoskeletal dynamics and cellular signaling pathways. Research has shown significant involvement of PLEKHG proteins in cell migration, adhesion, and proliferation, highlighting their significance in both normal physiology and disease states. PLEKHG proteins have emerged as important factors in cancer development and neurodegenerative conditions. Investigating PLEKHG protein mechanisms can reveal potential therapeutic targets and treatment strategies. Ongoing studies continue to uncover new functions and regulatory mechanisms of PLEKHG proteins in cellular processes. Research utilizing PLEKHG monoclonal antibodies from Santa Cruz Biotechnology contributes to advancing scientific understanding of cellular regulation and disease mechanisms.

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PLEKHG Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PLEKHG5 Antibody (5A9)

sc-517108mouse IgG2a κ896-995 (h)WB, IP, IF, IHC(P), ELISAh

new

(1)

PLEKHG CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PLEKHG1 CRISPR/Cas9 KO Plasmid (h)

sc-408703hGene KnockoutGFP0
(0)

PLEKHG1 HDR Plasmid (h)

sc-408703-HDRhHomology Directed RepairPuromycin0
(0)

PLEKHG1 Double Nickase Plasmid (h)

sc-408703-NIChGene KnockoutPuromycin0
(0)

PLEKHG1 Double Nickase Plasmid (h2)

sc-408703-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG1 CRISPR/Cas9 KO Plasmid (m)

sc-431895mGene KnockoutGFP0
(0)

PLEKHG1 HDR Plasmid (m)

sc-431895-HDRmHomology Directed RepairPuromycin0
(0)

PLEKHG1 Double Nickase Plasmid (m)

sc-431895-NICmGene KnockoutPuromycin0
(0)

PLEKHG1 Double Nickase Plasmid (m2)

sc-431895-NIC-2mGene KnockoutPuromycin0
(0)

PLEKHG2 CRISPR/Cas9 KO Plasmid (h)

sc-413048hGene KnockoutGFP0
(0)

PLEKHG2 HDR Plasmid (h)

sc-413048-HDRhHomology Directed RepairPuromycin0
(0)

PLEKHG2 Double Nickase Plasmid (h)

sc-413048-NIChGene KnockoutPuromycin0
(0)

PLEKHG2 Double Nickase Plasmid (h2)

sc-413048-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG2 CRISPR/Cas9 KO Plasmid (m)

sc-430377mGene KnockoutGFP0
(0)

PLEKHG2 HDR Plasmid (m)

sc-430377-HDRmHomology Directed RepairPuromycin0
(0)

PLEKHG2 Double Nickase Plasmid (m)

sc-430377-NICmGene KnockoutPuromycin0
(0)

PLEKHG2 Double Nickase Plasmid (m2)

sc-430377-NIC-2mGene KnockoutPuromycin0
(0)

PLEKHG3 CRISPR/Cas9 KO Plasmid (h)

sc-411863hGene KnockoutGFP0
(0)

PLEKHG3 HDR Plasmid (h)

sc-411863-HDRhHomology Directed RepairPuromycin0
(0)

PLEKHG3 Double Nickase Plasmid (h)

sc-411863-NIChGene KnockoutPuromycin0
(0)

PLEKHG3 Double Nickase Plasmid (h2)

sc-411863-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG3 CRISPR/Cas9 KO Plasmid (m)

sc-435213mGene KnockoutGFP0
(0)

PLEKHG3 HDR Plasmid (m)

sc-435213-HDRmHomology Directed RepairPuromycin0
(0)

PLEKHG3 Double Nickase Plasmid (m)

sc-435213-NICmGene KnockoutPuromycin0
(0)

PLEKHG3 Double Nickase Plasmid (m2)

sc-435213-NIC-2mGene KnockoutPuromycin0
(0)

PLEKHG4B CRISPR/Cas9 KO Plasmid (h)

sc-407381hGene KnockoutGFP0
(0)

PLEKHG4B Double Nickase Plasmid (h)

sc-407381-NIChGene KnockoutPuromycin0
(0)

PLEKHG4B Double Nickase Plasmid (h2)

sc-407381-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG5 CRISPR/Cas9 KO Plasmid (h)

sc-418543hGene KnockoutGFP0
(0)

PLEKHG5 HDR Plasmid (h)

sc-418543-HDRhHomology Directed RepairPuromycin0
(0)

PLEKHG5 Double Nickase Plasmid (h)

sc-418543-NIChGene KnockoutPuromycin0
(0)

PLEKHG5 Double Nickase Plasmid (h2)

sc-418543-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG5 CRISPR/Cas9 KO Plasmid (m)

sc-435355mGene KnockoutGFP0
(0)

PLEKHG5 HDR Plasmid (m)

sc-435355-HDRmHomology Directed RepairPuromycin0
(0)

PLEKHG5 Double Nickase Plasmid (m)

sc-435355-NICmGene KnockoutPuromycin0
(0)

PLEKHG5 Double Nickase Plasmid (m2)

sc-435355-NIC-2mGene KnockoutPuromycin0
(0)

PLEKHG6 CRISPR/Cas9 KO Plasmid (h)

sc-412479hGene KnockoutGFP0
(0)

PLEKHG6 HDR Plasmid (h)

sc-412479-HDRhHomology Directed RepairPuromycin0
(0)

PLEKHG6 Double Nickase Plasmid (h)

sc-412479-NIChGene KnockoutPuromycin0
(0)

PLEKHG6 Double Nickase Plasmid (h2)

sc-412479-NIC-2hGene KnockoutPuromycin0
(0)

PLEKHG6 CRISPR/Cas9 KO Plasmid (m)

sc-431880mGene KnockoutGFP0
(0)

PLEKHG6 HDR Plasmid (m)

sc-431880-HDRmHomology Directed RepairPuromycin0
(0)

PLEKHG6 Double Nickase Plasmid (m)

sc-431880-NICmGene KnockoutPuromycin0
(0)

PLEKHG6 Double Nickase Plasmid (m2)

sc-431880-NIC-2mGene KnockoutPuromycin0
(0)

PLEKHG CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PLEKHG1 CRISPR Activation Plasmid (h)

sc-408703-ACThGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 CRISPR Activation Plasmid (h2)

sc-408703-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 Lentiviral Activation Particles (h)

sc-408703-LAChGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 Lentiviral Activation Particles (h2)

sc-408703-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 CRISPR Activation Plasmid (m)

sc-431895-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 CRISPR Activation Plasmid (m2)

sc-431895-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 Lentiviral Activation Particles (m)

sc-431895-LACmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG1 Lentiviral Activation Particles (m2)

sc-431895-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 CRISPR Activation Plasmid (h)

sc-413048-ACThGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 CRISPR Activation Plasmid (h2)

sc-413048-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 Lentiviral Activation Particles (h)

sc-413048-LAChGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 Lentiviral Activation Particles (h2)

sc-413048-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 CRISPR Activation Plasmid (m)

sc-430377-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 CRISPR Activation Plasmid (m2)

sc-430377-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 Lentiviral Activation Particles (m)

sc-430377-LACmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG2 Lentiviral Activation Particles (m2)

sc-430377-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 CRISPR Activation Plasmid (h)

sc-411863-ACThGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 CRISPR Activation Plasmid (h2)

sc-411863-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 Lentiviral Activation Particles (h)

sc-411863-LAChGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 Lentiviral Activation Particles (h2)

sc-411863-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 CRISPR Activation Plasmid (m)

sc-435213-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 CRISPR Activation Plasmid (m2)

sc-435213-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 Lentiviral Activation Particles (m)

sc-435213-LACmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG3 Lentiviral Activation Particles (m2)

sc-435213-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG4B CRISPR Activation Plasmid (h)

sc-407381-ACThGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG4B CRISPR Activation Plasmid (h2)

sc-407381-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG4B Lentiviral Activation Particles (h)

sc-407381-LAChGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG4B Lentiviral Activation Particles (h2)

sc-407381-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 CRISPR Activation Plasmid (h)

sc-418543-ACThGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 CRISPR Activation Plasmid (h2)

sc-418543-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 Lentiviral Activation Particles (h)

sc-418543-LAChGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 Lentiviral Activation Particles (h2)

sc-418543-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 CRISPR Activation Plasmid (m)

sc-435355-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 CRISPR Activation Plasmid (m2)

sc-435355-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 Lentiviral Activation Particles (m)

sc-435355-LACmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG5 Lentiviral Activation Particles (m2)

sc-435355-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 CRISPR Activation Plasmid (h)

sc-412479-ACThGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 CRISPR Activation Plasmid (h2)

sc-412479-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 Lentiviral Activation Particles (h)

sc-412479-LAChGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 Lentiviral Activation Particles (h2)

sc-412479-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 CRISPR Activation Plasmid (m)

sc-431880-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 CRISPR Activation Plasmid (m2)

sc-431880-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 Lentiviral Activation Particles (m)

sc-431880-LACmGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG6 Lentiviral Activation Particles (m2)

sc-431880-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PLEKHG siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PLEKHG1 siRNA (h)

sc-95507hGene SilencingN/A0
(0)

PLEKHG1 shRNA Plasmid (h)

sc-95507-SHhGene SilencingPuromycin0
(0)

PLEKHG1 shRNA (h) Lentiviral Particles

sc-95507-VhGene SilencingPuromycin0
(0)

PLEKHG1 siRNA (m)

sc-152311mGene SilencingN/A0
(0)

PLEKHG1 shRNA Plasmid (m)

sc-152311-SHmGene SilencingPuromycin0
(0)

PLEKHG1 shRNA (m) Lentiviral Particles

sc-152311-VmGene SilencingPuromycin0
(0)

PLEKHG2 siRNA (h)

sc-97423hGene SilencingN/A0
(0)

PLEKHG2 shRNA Plasmid (h)

sc-97423-SHhGene SilencingPuromycin0
(0)

PLEKHG2 shRNA (h) Lentiviral Particles

sc-97423-VhGene SilencingPuromycin0
(0)

PLEKHG2 siRNA (m)

sc-152312mGene SilencingN/A0
(0)

PLEKHG2 shRNA Plasmid (m)

sc-152312-SHmGene SilencingPuromycin0
(0)

PLEKHG2 shRNA (m) Lentiviral Particles

sc-152312-VmGene SilencingPuromycin0
(0)

PLEKHG3 siRNA (h)

sc-92185hGene SilencingN/A0
(0)

PLEKHG3 shRNA Plasmid (h)

sc-92185-SHhGene SilencingPuromycin0
(0)

PLEKHG3 shRNA (h) Lentiviral Particles

sc-92185-VhGene SilencingPuromycin0
(0)

PLEKHG3 siRNA (m)

sc-152313mGene SilencingN/A
1
(0)

PLEKHG3 shRNA Plasmid (m)

sc-152313-SHmGene SilencingPuromycin
1
(0)

PLEKHG3 shRNA (m) Lentiviral Particles

sc-152313-VmGene SilencingPuromycin
1
(0)

PLEKHG4B siRNA (h)

sc-91766hGene SilencingN/A0
(0)

PLEKHG4B shRNA Plasmid (h)

sc-91766-SHhGene SilencingPuromycin0
(0)

PLEKHG4B shRNA (h) Lentiviral Particles

sc-91766-VhGene SilencingPuromycin0
(0)

PLEKHG5 siRNA (h)

sc-88767hGene SilencingN/A0
(0)

PLEKHG5 shRNA Plasmid (h)

sc-88767-SHhGene SilencingPuromycin0
(0)

PLEKHG5 shRNA (h) Lentiviral Particles

sc-88767-VhGene SilencingPuromycin0
(0)

PLEKHG5 siRNA (m)

sc-152314mGene SilencingN/A0
(0)

PLEKHG5 shRNA Plasmid (m)

sc-152314-SHmGene SilencingPuromycin0
(0)

PLEKHG5 shRNA (m) Lentiviral Particles

sc-152314-VmGene SilencingPuromycin0
(0)

PLEKHG6 siRNA (h)

sc-95843hGene SilencingN/A0
(0)

PLEKHG6 shRNA Plasmid (h)

sc-95843-SHhGene SilencingPuromycin0
(0)

PLEKHG6 shRNA (h) Lentiviral Particles

sc-95843-VhGene SilencingPuromycin0
(0)

PLEKHG6 siRNA (m)

sc-152315mGene SilencingN/A0
(0)

PLEKHG6 shRNA Plasmid (m)

sc-152315-SHmGene SilencingPuromycin0
(0)

PLEKHG6 shRNA (m) Lentiviral Particles

sc-152315-VmGene SilencingPuromycin0
(0)