plasmolipin Activators
Plasmolipin activators are a distinct group of molecules that interact with and enhance the biological activity of plasmolipin, which is also known as proteolipid protein (PLP). Plasmolipin is a major component of the myelin sheath, the insulating layer that surrounds nerve fibers in the central nervous system, and is vital for proper nerve conduction. The protein is integral to several cellular functions, including the formation and maintenance of myelin, as well as participating in the orchestration of the myelin structure. Plasmolipin activators work by binding to the protein and promoting its activity, which could have implications for the dynamics of myelin assembly and the overall integrity of myelinated nerve fibers.
The chemical architecture of plasmolipin activators is designed to engage with plasmolipin and facilitate its function. These activators may interact with the protein in a way that stabilizes its structure or enhances its interaction with other myelin components, thus promoting the proper assembly and maintenance of the myelin sheath. These compounds typically contain specific functional groups that enable their incorporation into the lipid-rich environment of the myelin membrane, where they can directly interact with plasmolipin. The interaction between plasmolipin activators and the protein can involve an array of non-covalent interactions, such as hydrogen bonding, van der Waals forces, and hydrophobic interactions, which collectively work to increase the efficiency of plasmolipin's role in myelin biogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, might directly stimulate the transcription factors that bind to the PLLP gene promoter, thereby potentially increasing the synthesis of plasmolipin. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a histone deacetylase inhibitor, could change the acetylation state of histones, potentially causing an increase in the transcriptional activity of the PLLP gene and subsequent plasmolipin production. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin, which activates adenylate cyclase to increase cAMP levels in cells, might stimulate signaling pathways that directly control the expression of the PLLP gene, thereby potentially leading to an increase in plasmolipin expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, through its broad gene regulatory effects, could potentially stimulate transcription factors or signaling pathways that directly control plasmolipin production by acting on the PLLP gene. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a glucocorticoid, might induce plasmolipin expression through glucocorticoid receptor-mediated effects on the transcriptional activity of the PLLP gene. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 (Cholecalciferol), by binding to the Vitamin D receptor (VDR), might stimulate the PLLP gene promoter, potentially leading to an increase in plasmolipin expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin Gallate, a polyphenol in green tea, could potentially increase the expression of plasmolipin through specific effects on cellular signaling pathways that control PLLP gene transcription. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride, through its action on several signaling pathways, might stimulate the transcriptional activity of the PLLP gene, potentially leading to an increase in plasmolipin expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid, a histone deacetylase inhibitor, could potentially increase the expression of plasmolipin by changing the acetylation state of histones in the region of the PLLP gene. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenolic compound, might stimulate the transcription of the PLLP gene through its specific effects on cellular signaling pathways or transcription factors, leading to a potential increase in plasmolipin expression. | ||||||