PIG3 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $62.00 $225.00 $779.00 | 24 | |
Nutlin-3 is an MDM2 antagonist that activates p5Similar to MI-219, the effects of Nutlin-3 on the p53 pathway may indirectly influence PIG3. | ||||||
p53 Activator III, RITA | 213261-59-7 | sc-202753 sc-202753A sc-202753B sc-202753C | 1 mg 10 mg 100 mg 500 mg | $112.00 $273.00 $1564.00 $5205.00 | 9 | |
RITA is a compound that activates p53 by disrupting the p53-MDM2 interaction. | ||||||
PRIMA-1 | 5608-24-2 | sc-200927 sc-200927A | 5 mg 25 mg | $102.00 $408.00 | 1 | |
PRIMA-1 (also known as PRIMA-1Met or APR-246) is a compound that reactivates mutant p53 and induces apoptosis. Since PIG3 is regulated by p53, PRIMA-1 may indirectly affect PIG3 activity. | ||||||
CP 31398 dihydrochloride | 259199-65-0 | sc-205270 sc-205270A | 10 mg 50 mg | $109.00 $434.00 | ||
CP-31398 is a compound that stabilizes and activates p53 by preventing its degradation. | ||||||
NSC 319726 | 71555-25-4 | sc-477736 | 10 mg | $159.00 | ||
NSC319726 is a small molecule that has been studied for its potential to reactivate p53 in cancer cells. | ||||||
Pifithrin-α hydrobromide | 63208-82-2 | sc-45050 sc-45050A | 5 mg 25 mg | $120.00 $300.00 | 36 | |
This derivative of Pifithrin-α(HBr) has been synthesized to enhance its stability and effectiveness in inhibiting PIG3. | ||||||
PRIMA-1MET | 5291-32-7 | sc-361295 sc-361295A | 10 mg 25 mg | $153.00 $325.00 | 5 | |
Researchers have developed various derivatives of PRIMA-1Met with improved pharmacological properties, aiming to enhance its p53-reactivating effects and potentially influence PIG3. | ||||||
SMER28 | 307538-42-7 | sc-222320 | 10 mg | $173.00 | ||
SMER28 is a small molecule that has been identified through a high-throughput screening approach to inhibit PIGIt may serve as a lead compound for further drug development. | ||||||