PGK2 Activators
PGK2 (Phosphoglycerate Kinase 2) is an enzyme variant specific to testis, playing an essential role in the glycolysis pathway within spermatozoa and is crucial for sperm development and function. Direct chemical activators of PGK2 are not commonly identified, but its activity and expression can be influenced indirectly by compounds that affect metabolic pathways, hormonal regulation, or spermatogenesis.
2-Deoxy-D-glucose (2-DG) and Metformin, which influence cellular glucose metabolism, could potentially impact PGK2 activity by altering the energy metabolism status in spermatogenic cells. Resveratrol, known for its effects on metabolic pathways, might also indirectly affect PGK2. Hormones such as Testosterone, FSH, and LH are critical regulators of spermatogenesis and could influence PGK2 expression or activity indirectly through their roles in testicular function and hormone regulation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor that mimics glucose deprivation, potentially influencing PGK2 activity. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
An AMPK activator, commonly used in diabetes treatment, could indirectly affect PGK2 by altering cellular energy metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to influence metabolic pathways and could indirectly affect PGK2 in spermatogenic cells. | ||||||
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $377.00 $2602.00 | ||
Essential for spermatogenesis; might indirectly influence PGK2 expression or activity. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Involved in cellular energy metabolism; could potentially influence PGK2 activity in spermatozoa. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $33.00 $77.00 $175.00 | 3 | |
Important for fatty acid metabolism in mitochondria; might impact energy metabolism and indirectly PGK2. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Influences various metabolic pathways; could indirectly affect PGK2 in spermatogenic cells. | ||||||
D-Aspartic acid | 1783-96-6 | sc-202562 | 1 g | $30.00 | ||
Involved in testosterone synthesis and may influence spermatogenesis, indirectly affecting PGK2. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essential for normal spermatogenesis and may play a role in regulating PGK2 activity or expression. | ||||||