Date published: 2026-4-25

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PDX Antibodies

Santa Cruz Biotechnology provides a broad selection of PDX Antibodies for studying patient-derived xenograft models. PDX Antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Patient-derived xenografts are critical for understanding tumor biology and therapeutic responses, as they maintain the heterogeneity of the original patient tumors. PDX Antibodies target specific proteins involved in cancer progression, metastasis, and treatment resistance, making them significant for translational research. By studying PDX models, researchers can gain insights into the molecular mechanisms underlying cancer and develop more effective treatment strategies. PDX Antibodies enable detailed analysis of tumor growth patterns and drug responses in preclinical studies. Understanding PDX models helps bridge the gap between laboratory findings and clinical applications. Investigating PDX models with monoclonal antibodies from Santa Cruz Biotechnology supports the development of personalized cancer treatments and advances in oncology research.

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PDX Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PDX-1 Antibody (B-11)

sc-390792mouse IgG1 κ1-140 (deletion 20-56) (h)WB, IP, IF, ELISAm, r, h
14
(7)

PDX-1 Antibody (E-5)

sc-390808mouse IgG2b κ1-140 (deletion 20-56) (h)WB, IP, IF, ELISAm, r, h
3
(1)

PDX-1 Antibody (E-8)

sc-398502mouse IgM κ95-110 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PDX CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDX-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400792-KO-2hGene KnockoutGFP0
(0)

PDX-1 HDR Plasmid (h2)

sc-400792-HDR-2hHomology Directed RepairPuromycin0
(0)

PDX-1 Double Nickase Plasmid (h)

sc-400792-NIChGene KnockoutPuromycin0
(0)

PDX-1 Double Nickase Plasmid (h2)

sc-400792-NIC-2hGene KnockoutPuromycin0
(0)

PDX CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDX-1 CRISPR Activation Plasmid (h)

sc-400792-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 CRISPR Activation Plasmid (h2)

sc-400792-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 Lentiviral Activation Particles (h)

sc-400792-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDX siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDX-1 siRNA (h)

sc-38760hGene SilencingN/A
1
(0)

PDX-1 shRNA Plasmid (h)

sc-38760-SHhGene SilencingPuromycin
1
(0)

PDX-1 shRNA (h) Lentiviral Particles

sc-38760-VhGene SilencingPuromycin
1
(0)

PDX-1 siRNA (m)

sc-38761mGene SilencingN/A0
(0)

PDX-1 shRNA Plasmid (m)

sc-38761-SHmGene SilencingPuromycin0
(0)

PDX-1 shRNA (m) Lentiviral Particles

sc-38761-VmGene SilencingPuromycin0
(0)

PDX-1 siRNA (r)

sc-108040rGene SilencingN/A
1
(0)

PDX-1 shRNA Plasmid (r)

sc-108040-SHrGene SilencingPuromycin
1
(0)

PDX-1 shRNA (r) Lentiviral Particles

sc-108040-VrGene SilencingPuromycin
1
(0)