Date published: 2025-11-22

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PDX-1 Antibodies

Santa Cruz Biotechnology offers a broad range of PDX-1 monoclonal antibodies for research focused on understanding PDX-1 protein function. PDX-1 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PDX-1, or pancreatic and duodenal homeobox 1, is a critical transcription factor involved in the development and function of pancreatic beta cells. PDX-1 plays a vital role in insulin gene expression and glucose homeostasis, making it essential for understanding diabetes and other metabolic disorders. Research involving PDX-1 continues to advance therapeutic strategies aimed at restoring insulin production and improving metabolic health. PDX-1 monoclonal antibodies enable detailed investigation of cellular pathways and molecular mechanisms in pancreatic development and function. Ongoing studies of PDX-1 expression patterns and interactions provide valuable insights into beta cell biology and potential therapeutic targets. Understanding PDX-1 regulation and its downstream effects helps illuminate new approaches for treating metabolic diseases. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of PDX-1's role in pancreatic function and metabolic health.

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PDX-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PDX-1 Antibody (B-11)

sc-390792mouse IgG1 κ1-140 (deletion 20-56) (h)WB, IP, IF, ELISAm, r, h
14
(7)

PDX-1 Antibody (E-5)

sc-390808mouse IgG2b κ1-140 (deletion 20-56) (h)WB, IP, IF, ELISAm, r, h
3
(1)

PDX-1 Antibody (E-8)

sc-398502mouse IgM κ95-110 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PDX-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDX-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400792-KO-2hGene KnockoutGFP0
(0)

PDX-1 HDR Plasmid (h2)

sc-400792-HDR-2hHomology Directed RepairPuromycin0
(0)

PDX-1 Double Nickase Plasmid (h)

sc-400792-NIChGene KnockoutPuromycin0
(0)

PDX-1 Double Nickase Plasmid (h2)

sc-400792-NIC-2hGene KnockoutPuromycin0
(0)

PDX-1 CRISPR/Cas9 KO Plasmid (m)

sc-422182mGene KnockoutGFP0
(0)

PDX-1 HDR Plasmid (m)

sc-422182-HDRmHomology Directed RepairPuromycin0
(0)

PDX-1 Double Nickase Plasmid (m)

sc-422182-NICmGene KnockoutPuromycin0
(0)

PDX-1 Double Nickase Plasmid (m2)

sc-422182-NIC-2mGene KnockoutPuromycin0
(0)

PDX-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDX-1 CRISPR Activation Plasmid (h)

sc-400792-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 CRISPR Activation Plasmid (h2)

sc-400792-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 Lentiviral Activation Particles (h)

sc-400792-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 Lentiviral Activation Particles (h2)

sc-400792-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 CRISPR Activation Plasmid (m)

sc-422182-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 CRISPR Activation Plasmid (m2)

sc-422182-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 Lentiviral Activation Particles (m)

sc-422182-LACmGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 Lentiviral Activation Particles (m2)

sc-422182-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PDX-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDX-1 siRNA (h)

sc-38760hGene SilencingN/A
1
(0)

PDX-1 shRNA Plasmid (h)

sc-38760-SHhGene SilencingPuromycin
1
(0)

PDX-1 shRNA (h) Lentiviral Particles

sc-38760-VhGene SilencingPuromycin
1
(0)

PDX-1 siRNA (m)

sc-38761mGene SilencingN/A0
(0)

PDX-1 shRNA Plasmid (m)

sc-38761-SHmGene SilencingPuromycin0
(0)

PDX-1 shRNA (m) Lentiviral Particles

sc-38761-VmGene SilencingPuromycin0
(0)

PDX-1 siRNA (r)

sc-108040rGene SilencingN/A
1
(0)

PDX-1 shRNA Plasmid (r)

sc-108040-SHrGene SilencingPuromycin
1
(0)

PDX-1 shRNA (r) Lentiviral Particles

sc-108040-VrGene SilencingPuromycin
1
(0)