SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ro 20-1724 | 29925-17-5 | sc-200709 sc-200709A sc-200709B | 100 mg 1 g 5 g | $85.00 $418.00 $1543.00 | 17 | |
Ro 20-1724 is a selective phosphodiesterase (PDE) inhibitor that modulates intracellular signaling pathways by stabilizing cyclic nucleotide levels. Its unique binding affinity to the PDE active site enhances the accumulation of cyclic AMP, leading to altered cellular responses. The compound's structural features promote specific interactions with the enzyme, influencing reaction kinetics and selectivity. This selectivity is crucial for dissecting complex biochemical networks and understanding cellular regulation. | ||||||
Calmodulin (human), (recombinant) | 73298-54-1 | sc-471287 | 1 mg | $232.00 | ||
Calmodulin (human, recombinant) is a calcium-binding protein that plays a pivotal role in cellular signaling by interacting with various target proteins. Its unique ability to undergo conformational changes upon calcium binding allows it to modulate enzyme activities, including phosphodiesterases. This dynamic interaction influences cyclic nucleotide metabolism, impacting downstream signaling pathways. The protein's versatility in binding and activating multiple targets underscores its significance in regulating diverse physiological processes. | ||||||
Ibudilast | 50847-11-5 | sc-203080 | 10 mg | $214.00 | 1 | |
Ibudilast functions as a phosphodiesterase (PDE) inhibitor, exhibiting a unique ability to modulate intracellular signaling by selectively interacting with cyclic nucleotide pathways. Its structure allows for specific binding to the active sites of PDE enzymes, altering their kinetics and enhancing the accumulation of cyclic AMP and cyclic GMP. This modulation can lead to intricate changes in cellular responses, influencing various biochemical cascades and regulatory mechanisms within the cell. | ||||||