Date published: 2026-1-8

1-800-457-3801

SCBT Portrait Logo
Seach Input

PDE Substrates

Santa Cruz Biotechnology now offers a broad range of PDE Substrates for use in various applications. PDE Substrates are pivotal in the study of phosphodiesterase (PDE) enzymes, which are responsible for the hydrolysis of cyclic nucleotides such as cAMP and cGMP, critical second messengers in numerous cellular signaling pathways. These substrates serve as essential tools for measuring PDE activity in various biological samples, enabling researchers to investigate the dynamics of cyclic nucleotide signaling in real-time. By using PDE Substrates, scientists can explore the regulation of key physiological processes, including cell proliferation, differentiation, metabolism, and neuronal signaling. The ability to accurately quantify PDE activity using specific substrates allows for detailed analysis of how cyclic nucleotide levels are modulated within cells and tissues under different conditions. This is particularly important for understanding the mechanisms by which cells respond to extracellular signals and maintain homeostasis. PDE Substrates are also employed in drug discovery and development to screen for potential PDE inhibitors or activators. Overall, PDE Substrates are indispensable in advancing our understanding of cellular signaling networks and the complex interplay between enzymes and their regulatory pathways. View detailed information on our available PDE Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2′-O-(N′-Methylanthraniloyl)guanosine-3′,5′-cyclic monophosphate sodium salt

83707-15-7sc-221695
10 µmol
$209.00
(0)

2'-O-(N'-Methylanthraniloyl)guanosine-3',5'-cyclic monophosphate sodium salt acts as a phosphodiesterase (PDE) inhibitor, characterized by its unique anthraniloyl moiety that enhances binding affinity to the enzyme. This compound exhibits a distinct allosteric modulation, impacting the enzyme's catalytic efficiency and altering the hydrolysis rate of cyclic GMP. Its interaction dynamics reveal a nuanced influence on cellular signaling pathways, contributing to the regulation of various physiological processes.

Bis(4-nitrophenyl)phosphate, sodium salt

4043-96-3sc-217768
sc-217768A
100 mg
1 g
$70.00
$371.00
(0)

Bis(4-nitrophenyl)phosphate, sodium salt functions as a phosphodiesterase (PDE) inhibitor, distinguished by its dual nitrophenyl groups that facilitate strong π-π stacking interactions with the enzyme's active site. This compound exhibits unique kinetic properties, enhancing substrate binding and altering the hydrolysis of cyclic nucleotides. Its structural features promote specific conformational changes in the enzyme, thereby modulating signaling pathways with precision and efficacy.